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Evaluarea manifestărilor clinico-paraclinice la pacienţii cu ciroză hepatică după tratamentul chirurgical prin devascularizarea azygo-portală şi splenectomie

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dc.contributor.author Tofan-Scutaru, Liudmila
dc.contributor.author Cazacov, Vladimir
dc.contributor.author Dumbrava, Vlada-Tatiana
dc.contributor.author Cojuhari, Maria
dc.contributor.author Alexa, Valeria
dc.date.accessioned 2019-12-09T15:45:44Z
dc.date.available 2019-12-09T15:45:44Z
dc.date.issued 2014
dc.identifier.citation TOFAN-SCUTARU, Liudmila, CAZACOV, Vladimir, DUMBRAVA, Vlada-Tatiana, COJUHARI, Maria, ALEXA, Valeria. Evaluarea manifestărilor clinico-paraclinice la pacienţii cu ciroză hepatică după tratamentul chirurgical prin devascularizarea azygo-portală şi splenectomie. In: Sănătate Publică, Economie şi Management în Medicină. 2014, nr. 5(56), pp. 128-132. ISSN 1729-8687. en_US
dc.identifier.issn 1729-8687
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/7239
dc.identifier.uri http://revistaspemm.md/wp-content/uploads/2019/05/cm5_56_2014.pdf
dc.description Departamentul Medicină Internă, Universitatea de Stat de Medicină şi Farmacie Nicolae Testemiţanu, Catedra Chirurgie nr. 2, USMF N. Testemiţanu, IMSP Spitalul Clinic Republican, Facultatea Medicină Generală, USMF N. Testemiţanu, Conferinţa Naţională de Gastroenterologie și Hepatologie cu participare internaţională 20 iunie 2014 Chişinău, Republica Moldova en_US
dc.description.abstract The study group, under which this research has been carried out, is made up of 47 patients who had been diagnosed with cirrhosis of different etiologies and significant splenomegaly within the portal hypertension, complicated with severe hypersplenism. It was noted that before surgery, in all patients was present the severe hypersplenism syndrome, in 48.9 % of the patients was present the hepatocellular insufficiency syndrome, in 27.6% of the patients was present the cholestasis syndrome, in 57.9 % of the patients was present cytolytic syndrome. After surgery, there was an improvement of the blood count indices by increasing the number of red blood cells, platelets, leukocytes and hemoglobin in all patients, was also noticed an improvement of the liver synthetic function with a statistically significant increase of prothrombin and fi brinogen. We also observed clinical improvement and the decrease of the frequency of complications of liver cirrhosis. The surgical approach showed the benefits in the clinical and laboratory evolution of patients with cirrhosis of different etiology and splenomegaly secondary to portal hypertension complicated with severe hypersplenism. en_US
dc.description.abstract Представлены результаты исследования 47 пациентов с диагнозом цирроз печени различной этиологии и значительной спленомегалией, в рамках портальной гипертензии, осложненной тяжелым гиперспленизмом. До операции, в 48,9% случаев отмечен синдром печёночной недостаточности, в 27,6% случаев присутствовал синдром холестаза и в 57,9% случаев – цитолитический синдром. После операции было установлено улучшение общего анализа крови, с повышением количества эритроцитов, тромбоцитов, лейкоцитов и гемоглобина у всех пациентов, а также замечено улучшение синтетической функции печени со статистически значимым увеличением уровня протромбина и фибриногена. Также было обнаружено улучшение клинических проявлений и уменьшение осложнений цирроза печени. Хирургический подход к пациентам с циррозом различной этиологии и спленомегалией в рамках портальной гипертензии, осложненной тяжелым гиперспленизмом, приносит пользу в эволюции клинико-параклинических проявлений.
dc.language.iso ro en_US
dc.publisher Asociația Obștească ”Economie, Management și Psihologie în Medicină” din Republica Moldova en_US
dc.subject cirrhosis en_US
dc.subject clinical and paraclinical characteristics en_US
dc.subject devascularization en_US
dc.subject splenectomy en_US
dc.subject.mesh Liver Cirrhosis--therapy en_US
dc.subject.mesh Liver Cirrhosis--surgery en_US
dc.subject.mesh Liver Cirrhosis--physiopathology en_US
dc.subject.mesh Splenectomy en_US
dc.subject.mesh Ligation en_US
dc.title Evaluarea manifestărilor clinico-paraclinice la pacienţii cu ciroză hepatică după tratamentul chirurgical prin devascularizarea azygo-portală şi splenectomie en_US
dc.title.alternative Evaluation of the clinical and paraclinical manifestations in patients with liver cirrhosis after surgical treatment by azygo-portal devascularization and splenectomy en_US
dc.title.alternative Оценка клинических и параклинических проявлений у пациентов с циррозом печени после операции по азиго-портальной деваскуляризации и спленэктомии en_US
dc.type Article en_US


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