Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

О некоторых возможностях улучшения регенеративных процессов роговицы глаза кроликов при её ожогах щёлочью в эксперименте

Show simple item record

dc.contributor.author Herasymyuk, I. E.
dc.contributor.author Romaniuk, T. I.
dc.date.accessioned 2020-01-27T09:03:59Z
dc.date.available 2020-01-27T09:03:59Z
dc.date.issued 2014
dc.identifier.citation HERASYMYUK, I., E., ROMANIUK, T., I. О некоторых возможностях улучшения регенеративных процессов роговицы глаза кроликов при её ожогах щёлочью в эксперименте. In: Curierul Medical. 2014, nr. 2(57), pp. 21-24. ISSN 1875-0666. en_US
dc.identifier.issn 1857-0666
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/7331
dc.identifier.uri http://moldmedjournal.md/wp-content/uploads/2016/09/79.pdf
dc.description Department of Anatomy, I. Ya. Gorbachevskiy State Medical University of Ternopol, Ukraine en_US
dc.description.abstract Background: Nowadays peptide bioregulators, stimulating repair processes, accelerating the substitution of necrotizing tissue with fibrous tissue and facilitating active access of young low-differentiated cellular elements between the corneal plates, reprezent a promising way of treating damaged cornea including its chemical burns. A well-known fact is that biological tissues exhibit a similar activity not only due to alive cells but also homogenates and extracts from them. Material and methods: The experiments have been performed on 24 rabbits. Each animal has been subject to a corneal burn with alkali (10% NaOH). Time of exposition for alkali was 10 seconds. To a half of the animals corneal burn correction was done with the help of cryophilic pig skin extract. Beginning with the first day of the experiment the extract of cryophilic pig skin was applied into the conjunctiva sac 1 drop after every 2 hours, during three days. Other 12 rabbits didn’t benefit from the extract correction. Results: The results obtained proved that using cryophilic pig skin extract allowed to improve significantly regeneration processes in cornea tissues after alkali burn. Epithelialization of a damaged area is fulfilled faster and better. It is demonstrated by the increase in the number of epithelial cells and their earlier differentiation as well as the increase of regulation of connective-tissue fibers leading to a more effective improvement of the optical features of the damaged area. Conclusions: It is assumed that this correction method enables the surface epithelium to regenerate due to division and migration of cornea basement epithelial cells as well as transformation and centre-oriented movement of limbus cambial (stem) cells that has already been mentioned in previous publications. en_US
dc.language.iso ru en_US
dc.publisher The Scientific Medical Association of the Republic of Moldova en_US
dc.relation.ispartof Curierul Medical
dc.subject cornea en_US
dc.subject burns en_US
dc.subject alkaline en_US
dc.subject regeneration en_US
dc.subject.mesh Cornea--physiopathology en_US
dc.subject.mesh Cornea--physiology en_US
dc.subject.mesh Cornea--drug effects en_US
dc.subject.mesh Eye Burns--therapy en_US
dc.subject.mesh Cell- and Tissue-Based Therapy en_US
dc.subject.mesh Alkalies--adverse effects en_US
dc.subject.mesh Rabbits en_US
dc.subject.mesh Regeneration--drug effects en_US
dc.subject.mesh Wound Healing--drug effects en_US
dc.title О некоторых возможностях улучшения регенеративных процессов роговицы глаза кроликов при её ожогах щёлочью в эксперименте en_US
dc.title.alternative Some improvement opportunities of regenerative processes of rabbit cornea after experimental alkaline burns en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account

Statistics