Abstract:
Background: Onychomycosis is one of the current medico-social challenges. The article deals with the advantages of combined comprehensive
therapy rendered to patients with onychomycoses using systemic antimycotics and vitamin agent Wolvit over standard therapeutic regimen determined
by a comparative study of two groups.
Material and methods: We observed 43 patients with onychomycosis of hands and feet: the main group (33 patients) received Wolvit 5 mg per day and
systemic antimycotic in standard dosage, control group (10 persons) – systemic antimycotic. The course of treatment was 1.5 months for onychomycosis
of the hands and 3 months for onychomycosis of the feet. All patients underwent a comprehensive clinical and laboratory examination. Mycological
research was on the fourth, sixth, eighth, tenth, twelfth and sixteenth weeks of treatment.
Results: The administration of vitamin agent Wolvit together with systemic antimycotics allows to achieve a significant improvement of nail plate
structure as it acquires even light pink translucent color, glossy surface, smooth and thick free edge, normotrophic structure. Participation of biothinum
in the formation of keratine, necessary for the development of hair matrix and nail plate, results in acceleration of healthy nail growth in patients with
onychomycoses. Biothinum is also a source of sulphur, which transports sulphur into the skin and its accessory organs, contributing to collagen formation
and therefore eliminates signs of early hair depigmantation, normalizes sebaceous glands function and exerts a positive impact on the structure of skin
and its accessory organs (hair, nails).
Conclusions: The obtained results show that the developed complex is effective, safe and allows to achieve both clinical and etiologic recovery
Description:
Institute of Dermatology and Venerology, National Academy of Medical Sciences of Ukraine, Kiev, Ukraine
