Abstract:
The purpose of the work consists in obtaining the methods of treatment of chronic viral hepatitis C even in a situation when the patients have
contraindications to the administration of standard antiviral therapy, and in improving the biochemical parameters and reducing the duration of
hospitalization of the children with chronic viral hepatitis C. The presented materials demonstrate the effectiveness of an original method of treatment
of viral hepatitis C in the case of high cytolysis associated with unbalanced diabetes, renal decompensation, non-viral autoimmune diseases, epilepsy
and other diseases, which have contraindications to the administration of antiviral therapy. The basic therapy has been supplemented by the national
phytopreparation Pacovirin in capsules with antiviral, immunomodulatory, antioxidant and interferonogenic activity. The efficacy of Pacovirin has been
assessed on the basis of clinical, virological, immunological and biochemical indices. At the same time the analysis and evaluation of the results in the
context of modern literature sources concerning the treatment of chronic hepatitis C in children with contraindications to standard antiviral therapy
has been performed. The obtained results demonstrate an increased effectiveness of the treatment that is manifested by more rapid normalization of
clinical and laboratory indices.
