Particularităţile tratamentului cu Ceftriaxon a pielonefritei acute la bolnavii cu diabet zaharat

Abstract

Summary. Pyelonephritis in patients with diabetes mellitus is a serious disease both from the endocrinological and urological aspects, because the inflammatory diseases of the kidney and urinary pathways in patients with diabetes mellitus is four times more frequent than in non-diabetics and it is characterized by a severe development , usually complicated by renal failure and urosepsis, being a leading cause of death. The late hospitalization, the unclear clinical picture, the late diagnostics and the inadequate treatment of these patients determine the development of severe forms of AP. The association of these two severe diseases endangers the patients’ life. This determined us to make a retrospective evaluation of the obtained data and to give treatment indications of AP with ceftriaxone. Cephalosporins of third generation, differ greatly from penicillin and cephalosporins of the preceding generations by their increased efficiency from the majority of enterobacteria, by their stability to the beta-lactamose action of gram-negative bacteria. In conclusion we can say that ceftriaxone has a specific action in the therapy of acute pyelonephritis.