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Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species

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dc.contributor.author Balan, Greta
dc.contributor.author Burduniuc, Olga
dc.date.accessioned 2020-05-26T05:44:47Z
dc.date.available 2020-05-26T05:44:47Z
dc.date.issued 2020
dc.identifier.citation BALAN, Greta, BURDUNIUC, Olga. Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species. In: The Moldovan Medical Journal. 2020, vol. 63, no 1, pp. 3-7. ISSN 2537-6373. DOI: 10.5281/zenodo.3685641 en_US
dc.identifier.issn 2537-6373
dc.identifier.issn 2537-6381
dc.identifier.uri http://moldmedjournal.md/wp-content/uploads/2020/06/Mold-Med-J-March-2020-Vol-63-No-1-Full-Issue-version-5-of-10-06-20.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/9824
dc.identifier.uri https://doi.org/10.5281/zenodo.3685641
dc.description Department of Microbiology and Immunology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Department of Laboratory Diagnostic in Public Health, National Agency for Public Health, Chisinau, the Republic of Moldova en_US
dc.description.abstract Background: Biofilms are surface-attached groups of microbial cells that are embedded in an extracellular matrix. One of the main features of biofilms is their resistance to antimicrobial drugs; therefore, the biofilm-based infections are extremely difficult to treat. This study aimed to investigate the biofilmforming capacity of Staphylococcus spp. and Candida spp. strains isolated from collected clinical samples, as well as to assess their antibiotic susceptibility. Material and methods: The study was conducted on 134 strains of Staphylococcus spp. and 147 strains of Candida spp. isolated from various clinical specimens. Both biofilm formation and antibiotic susceptibility of the isolated strains were studied using contemporary standardized microbiological methods. Results: The results of the study showed a high biofilm-forming capacity among the clinical strains of Staphylococcus spp. and Candida spp., as well as a higher level of antibiotic resistance in biofilm-producing strains compared to biofilm non-producing ones. Conclusions: The high rates of antibiotic resistance and biofilm-forming capacity of strains represent a major public health challenge. The study showed a strong correlation between biofilm formation and antimicrobial resistance patterns. en_US
dc.language.iso en en_US
dc.publisher The Scientific Medical Association of the Republic of Moldova en_US
dc.relation.ispartof The Moldovan Medical Journal
dc.subject Staphylococcus spp. en_US
dc.subject Candida spp en_US
dc.subject biofilm formation en_US
dc.subject antimicrobial resistance en_US
dc.subject.ddc UDC: 579.861.2+582.282.23+615.015.8 en_US
dc.subject.mesh Drug Resistance, Microbial en_US
dc.subject.mesh Drug Resistance, Bacterial en_US
dc.subject.mesh Biofilms en_US
dc.subject.mesh Staphylococcus en_US
dc.subject.mesh Candida en_US
dc.title Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species en_US
dc.type Article en_US


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