IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Hemodynamic indicators in the superior mesenteric vein in patients with hepatic cirrhosis 
    Cobîleanschii, Eugeniu; Cobîleanscaia, Liubov (CEP Medicina, 2025)
    Introduction. Blood from the small intestine drains through the superior mesenteric vein. Defective blood flow, caused by hemodynamic deviations, lead to intestinal ischemia. Under these conditions, the cells of the ...
  • Correlations between echocardiographic findings and SPECT CT as a predective tool for chronic thromboembolic pulmonary hypertension in post-pulmonary embolism patients 
    Sorici, Galina; Diaconu, Nadejda; Civirjic, Irina; Ivanes, Igor; Gorohova, Marina; Plugaru, Ana; Grosu, Aurel (CEP Medicina, 2025)
    Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe but potentially treatable complication of pulmonary embolism (PE). SPECT CT has emerged as a non-invasive modality capable of detecting residual ...
  • Molecular mechanisms of neuronal aging and neurodegeneration 
    Demidova, Inga; Șaptefrați, Lilian (CEP Medicina, 2025)
    Background. Aging of the nervous system is accompanied by complex molecular changes that contribute to the development of neurodegenerative diseases. Understanding these mechanisms is crucial for developing effective ...
  • The role of endothelins in cancer progression: recent insights and therapeutic opportunities 
    Cazacu, Felicia; Sardari, Veronica; Munteanu, Roman; Rudic, Ciprian; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Endothelins (ETs) and their receptors (ETAR and ETBR) play a significant role in cancer progression, influencing processes such as proliferation, invasion, and metastasis. The endothelin axis contributes to ...
  • Mitochondrial calcium regulation in Alzheimer`s disease 
    Casian, Andreea; Sardari, Veronica (CEP Medicina, 2025)
    Background. Calcium ions (Ca²⁺) play an essential role in neuronal function, contributing to synaptic transmission, interneuronal communication, and neuroglial interactions. Mitochondria regulate the intracellular ...
  • Telomere shortening as a mechanism for the induction of neurodegenetative diseases 
    Casian, Andreea; Sardari, Veronica; Stratulat, Silvia; Munteanu, Roman; Cojoc, Daniela; Tagadiuc, Olga (CEP Medicina, 2025)
    Background. Telomeres are considered the "cellular biological clock" because their length could determine the possible number of cell divisions. Telomerase plays a role in maintaining telomere length. Telomerase ensures ...
  • Review: the role of color Doppler ultrasound in the evaluation of thyroid nodules 
    Calistru, Natalia; Țarălungă, Tatiana; Vangheli, Ludmila (CEP Medicina, 2025)
    Background: Thyroid nodules are commonly detected in clinical practice, with a significant portion being benign, but a small percentage harbor malignancy. Accurate evaluation of these nodules is crucial for guiding ...
  • Nasal permeability in inflammatory rhinosinusal diseases in children 
    Maniuc, Mihail; Danilov, Lucian; Ababii, Polina; Nacu, Viorel; Furculița, Daniel; Bugan, Maria; Crețu, Carolina; Vishnumaya, Sureshan (CEP Medicina, 2025)
    Introduction: Rhinosinusal inflammatory diseases constitute a current problem of contemporary rhinology. Rhinitis, sinusitis seriously affect the physiological functions of the nose, including the most important of them, ...
  • Correlation between CD45 expression and clinical-pathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus 
    Brînza, Dumitru (CEP Medicina, 2025)
    Introduction. This study investigates the correlation between CD45 expression and clinicalpathological variables in invasive ductal breast carcinoma associated with type 2 diabetes mellitus. CD45, an immune regulator, was ...
  • Neuroprotective effects of ethanolic extracts from Solanum macrocarpon in a zebrafish model of scopolamine-induced Alzheimer's disease-related dementia 
    Brînza, Ion; Guliev, Corina A.; Oluwabukola Oresanya, Ibukun; Nazli Gok, Hasya; Erdogan Orhan, Ilkay; Hrițcu, Lucian (CEP Medicina, 2025)
    Introduction. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and oxidative stress. Natural bioactive compounds with antioxidant and neuroprotective properties have ...
  • Anatomical variability of the deep femoral artery 
    Botnaru, Doina; Zorina, Zinovia; Babuci, Angela; Catereniuc, Ilia; Botnari, Tatiana (CEP Medicina, 2025)
    Introduction: The deep femoral artery (DFA) serves as a crucial „turning point” between collateral circulation of the pelvis and that of the lower limb (LL), playing a determinant role not only in femoropopliteal axis ...
  • Variability of the paired visceral branches of the abdominal aorta 
    Botnari, Tatiana; Babuci, Angela; Zorina, Zinovia; Catereniuc, Ilia; Botnaru, Doina; Ostahi, Nadia (CEP Medicina, 2025)
    Introduction: The demand for an individualized approach in interventional surgery of abdominal cavity organs has recently increased. Due to various surgical techniques and large number of surgeries, including kidney ...
  • Specific features of the facial nerve trunk 
    Babuci, Angela; Zorina, Zinovia; Bendelic, Anastasia; Ostahi, Nadia; Botnari, Tatiana; Botnaru, Doina; Lehtman, Sofia; Motelica, Gabriela; Nastas, Liliana; Calancea, Sergiu (CEP Medicina, 2025)
    Introduction: The facial nerve trunk (FNT) is vulnerable to iatrogenic injures in surgery of the retromandibular region, particularly in mastoidectomy. Variation of the FNT number, topography and course increase the risk ...
  • Current events in liver transplatology 
    Zavtoni, Ana-Maria; Harea, Gheorghe (CEP Medicina, 2025)
    Background. Liver transplantation is a surgical procedure that involves removing a diseased liver and replacing it with a healthy liver from another person, called a donor. This procedure is used when the liver is unable ...
  • Endocrine disruptors - a current problem for the human body 
    Zavtoni, Mariana; Miron, Inga; Bernic, Vladimir; Corețchi, Roman (CEP Medicina, 2025)
    Introduction. Endocrine disruptors are chemical substances that cause adverse effects in an organism or its offspring, leading to morphological and physiological changes and contributing to the deterioration of functional ...
  • Stem cells in regenerative dentistry: actualities and future directions 
    Țurcan, Paula; Capcelea, Svetlana (CEP Medicina, 2025)
    Introduction. Stem cells are pluripotent cells capable of differentiating into various specialized cell types, making them a promising tool in regenerative dentistry. Their potential to regenerate different parts of the ...
  • Cardiorenal syndrome and cellular therapeutic perspectives: risk factor identification for targeted interventions 
    Tonofa, Maria; Purteanu, Lilia; Benescu, Irina; Cozma, Octavian; Grib, Livi (CEP Medicina, 2025)
    Introduction. Cardiorenal syndrome (CRS) is a complex pathological condition that highlights the bidirectional relationship between heart failure and chronic kidney disease. This interdependence is driven by multiple ...
  • COPD and comorbidities in the Republic of Moldova 
    Corlăteanu, Alexandru; Covanțev, Serghei; Scutaru, Eugenia; Rusu, Doina; Botnaru, Victor; Corlăteanu, Olga; Siafakas, Nikolaos (Turkish Respiratory Society, 2022)
    BACKGROUND AND AIM: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide, and the majority of patients have at least one comorbid condition of clinical significance. Therefore, we ...
  • Efficiency of different multidimensional indexes for the assessment of the risk of exacerbations in patients with COPD 
    Corlăteanu, Alexandru; Scutaru, Eugenia; Rusu, Doina; Corlăteanu, Olga; Covanțev, Serghei; Botnaru, Victor (European Respiratory Journal, 2020)
    Background: COPD is a mainly chronic respiratory disease, a great number of patients suffer from exacerbations, which are defined as an acute worsening of respiratory symptoms requiring a change in treatment. Exacerbations ...
  • Review of rodent hypertension glaucoma models 
    Țarălungă, Tatiana; Iacubițchii, Maria; Paduca, Ala; Nacu, Viorel (CEP Medicina, 2025)
    Background: Hypertension is a major risk factor for glaucoma, a leading cause of irreversible blindness. Elevated intraocular pressure (IOP) is central to glaucoma pathology, often causing optic nerve damage and retinal ...