IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Disruption of the immune response in patients with obesity during COVID-19 
    Zahlîstnîi, Bogdan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Obesity was one of the frequent comorbidities in hospitalized patients with SARSCoV-2 infection. The recent studies of Covid-19 outcomes have noticed a correlation between obesity and more severe clinical ...
  • Porto-systemic venous shunts 
    Smerea, Viorel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Portosystemic shunts are abnormal vessels that allow portal blood to enter the systemic circulation without passing through the liver. They can be extrahepatic, where the vascular abnormalities are outside ...
  • The significant impact of artificial intelligence in TAVI 
    Tofan, Lucian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Currently, TAVI represents a benchmark in the treatment of patients with severe aortic stenosis, becoming a durable and preferred option compared to the traditional SAVR method. The success of TAVI significantly ...
  • Study of risk factors in patients with aortic stenosis 
    Vlad, Ariana; Mazur-Nicorici, Lucia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Aortic valve stenosis is commonly considered a degenerative disorder with no recommended preventive intervention. With increased life expectancy and aging of the population, aortic stenosis is now one of the ...
  • The impact of COVID-19 on patients with non-Hodgkin lymphoma 
    Dediu, Luminița (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Patients diagnosed with coronavirus 2019 (COVID-19) disease during hematological malignancies have been described as having a poor outcome, with only a few reports specifically addressing patients with lymphoma. ...
  • Genetic aspects of thrombophilia in pregnancy 
    Antoci, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Thrombophilia represents a condition that increases blood coagulability and the risk of clots. Physiological changes during pregnancy, such as excess fibrinogen synthesis and increased concentration of ...
  • Unraveling the molecular signaling pathways in glial tumors with methylated MGMT promoters 
    Croitoru, Dan; Andronachi, Victor; Andrușca, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Most gliomas are typically assessed using imaging methods. A recent advancement in this regard involves the integration of biomarkers in conjunction with imaging techniques, such as 18F-FDG-PET-based radiomics ...
  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Dietary habits of patients with ischemic heart disease 
    Abraș, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ischemic heart disease continues to be the leading cause of mortality, morbidit y and high hospitalization rates in both high-income and developing countries. According to data from the World Health Organization, ...
  • Personalized medicine and cardiovascular diseases 
    Sooltan, Abdool Rahim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There was a remarkable growth in scientific publication on personalized medicine within the past few years in the field of cardiovascular disease. In the era of personalized/precision medicine the combination ...
  • Diagnosis and treatment: insights on a clinical case of visceral sarcoidosis 
    Benchebchoub, Ouassim (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Sarcoidosis is a systemic disease involving formation of granulomas that can affect the lungs, skin or lymph nodes, and less commonly the eyes, heart, liver and brain, though any organ can be affected. The ...
  • Challenges and opportunities of the artificial intelligence in respiratory medicine 
    Stafi, Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Artificial Intelligence is a mechanism capable of actively perceiving the surrounding environment, taking initiatives to maximize the chances of successfully achieving its objectives. Additionally, it can ...
  • Wheat-dependent exercise-induced anaphylaxis 
    Cebotari, Iuliana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a rare food allergy that can lead to severe anaphylactic reactions. The reactions usually occur 1–4 hours after consuming wheat, followed by physical ...
  • Strategies and approaches adopted by community nurses from the Republic of Moldova in promoting a healthy lifestyle 
    Chitoroagă, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Community nurses play a vital role in promoting the health and well-being of the population, particularly in adopting and maintaining a healthy lifestyle. In the Republic of Moldova, these medical professionals ...
  • Indications and limits of gene therapy 
    Doni, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gene therapies represent advanced medical tools that aim to fix or improve genes by correcting mutations or making modifications at a specific site. While there are several successful protocols, it remains a ...
  • Hyperferritinemia in liver diseases - diagnosis and controversies 
    Faraj, Shehab (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ferritin is a protein that plays a crucial role in iron storage and regulation within the body. It is found primarily within cells, particularly in the liver, spleen, bone marrow, and other tissues that store ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Epilepsy associated with cerebral toxoplasmosis 
    Olaru, Natalia; Dragan, Diana; Vataman, Anatolie; Chiosa, Vitalie (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Parasitic infections of the central nervous system (CNS) are an acquired cause of epileptic seizures and epilepsy in countries with low and medium economic incomes, including the Republic of Moldova. Cerebral ...
  • RpoB S450L mutation and transmission features of MDR mycobacterium tuberculosis strains in the Republic of Moldova. 
    Chesov, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The Republic of Moldova (RM) faces a significant challenge with a high prevalence of multidrug-resistant tuberculosis (MDR-TB). Aim of study. This study aims to explore the potential impact of rpoB S450L ...