IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • Bullous pemphigoid, clinical aspects and treatment 
    Caradjova, Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bullous pemphigoid is a chronic, potentially fatal autoimmune skin disease that results in generalized pruritic bullous eruptions in older patients. Local and systemic glucocorticosteroid drugs are prescribed ...
  • Role of neurofilament light chain in neurological disease 
    Vasilieva, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Neurofilament light chain (NF-L) is a cytoplasmic protein highly expressed in large-caliber myelinated axons. The degree of axonal damage in a variety of neurological disorders, including inflammatory, ...
  • Medical and social patterns of pelvic inflammatory disease in the Republic of Moldova 
    Căldare, Arina; Grăjdean, Victor; Vicol, Adrian; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pelvic inflammatory disease (PID) represents a significant medical and social problem. It encompasses conditions such as endometritis, salpingitis, hydrosalpinx, pyosalpinx, and tubo-ovarian abscess. The ...
  • A comprehensive approach to improving management in postpartum hemorrhage 
    Gordaș, Cătălin; Gligor. Irina; Luchianic. Vasile; Cemortan. Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity, which needs a vigilant approach for early qualified diagnosis and timely multidisciplinary management. Pregnant women at ...
  • Chorio-villous mesenchymal stromal dysplasia in the course of pregnancies 
    Grosu, Eugenia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stromal dysplasia is a developmental anomaly of the placenta that is characterized microscopically by dilated stem villi with a myxoid or hydropic appearance, cisterna lacunae, and lack of ...
  • Case report of a perforated intrauterine device into sigmoid colon 
    Prepeliță, Mădălina; Lavric, Irina; Găină, Gheorghe (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intrauterine devices (IUD) have become one of the most popular birth control methods worldwide. Uterine perforation is an uncommon complication of IUD, with an incidence 1: 1,000 insertions. Perforation may ...
  • Diagnostic challenges in unusual gynecological synchronous tumor: a pathologist’s perspective 
    Ciobanu, Miruna-Olguța; Toma, Loredana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Ovarian carcinosarcoma (OCS) is an uncommon high-risk malignant biphasic neoplasm consisting of morphologically high-grade carcinomatous and sarcomatous tissue elements. OCS has an incidence of 2.5% (4 cases ...
  • Chronic suppurative otitis media complicated with facial paresis 
    Iutis, Vlada; Didencu, Alexandru; Noroc, Iurie; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic otitis media (COM) is a recurrent infection affecting the middle ear and/or mastoid air cells, often accompanied by a perforated tympanic membrane (TM). Additionally, COM may progress to a condition ...
  • Cochlear implantation in deaf-mute adult with partial optic nerve atrophy 
    Istrati, Andriana; Noroc, Iurie; Vetricean, Sergiu; Sencu, Eusebiu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Congenital deafness together with that acquired at a young age represent important pathological conditions, with an incidence of about 1-3 cases per 1000 live births, being diagnosed relatively late has ...
  • Cell therapy in chronic rhinosinusitis in children 
    Al Faraj, Iunis (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Chronic Rhinosinusitis is one of the most common chronic diseases worldwide, having an incidence between 1%-12% Globally and an incidence of 10.9% in Europe. CRS (Chronic Rhinosinusitis) is an underestimated ...
  • Histogenesis and specific morphological aspects of the photoreceptors 
    Iusiumbeli, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. People rely on visual cues to navigate the world around them. Vision begins with the detection of light by photoreceptors of the retina - the light sensitive cells of the eye. Photoreceptor types are defined ...
  • Endocrine changes and menstrual dysfunctions in adolescent girls with obesity 
    Solcanu, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent decades, there has been a significant increase in the obesity rate among adolescent girls. According to the specialized literature, obesity induces hormonal changes that have consequences on sexual ...
  • HPV status and associated precursor lesion in vulvar squamous cell carcinoma 
    Butnaru, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There are distinctive precursor lesions related to vulvar squamous cell carcinoma (VSCC) that are associated with high-risk human papillomavirus (HPV) type 16,18 specifically vulvar intraepithelial neoplasia ...
  • Mesenchymal stem cell-derived exosomes and their antineoplastic potential 
    Louka, George (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stem cells (MSC) are pluripotent cell types derived from mesenchyme able to differentiate and proliferate into a variety of tissues. Exosomes derived from MSC exhibit a round morphology (40-160 ...
  • New concepts of treatment of carpal tunnel syndrome 
    Lungu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Carpal tunnel syndrome is the most common form of focal peripheral compressive mononeuropathy of the median nerve accompanied by pain, paresthesia, weakness along the nerve's path and represents approximately ...
  • Pharmacological approach to Wernicke-Korsakoff syndrome 
    Cernov, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wernicke-Korsakoff Syndrome (WKS) represents, in 16-38% of cases, a clinical triad of confusion, ataxia and nystagmus. Conceptualized as two distinct syndromes, 85% of survivors of the untreated acute phase ...
  • Particularities of the action of the inhibitors of the renin-angiotensin-aldosterone system in men and women 
    Nicolenco, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The renin-angiotensin-aldosterone system (RAAS) plays a significant role in cardiovascular pathology, including arterial hypertension (HTA). It has been demonstrated that endogenous sex hormones interact ...
  • Morphological and immunohistochemical features in the differential diagnosis of hydatiform mole 
    Rusnac, Ioana Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hydatidiform mole is a pathological pregnancy that belongs to the gestational trophoblastic diseases group. During histomorphological lesion examination, differentiating between molar and non-molar lesions ...
  • Prospects for obtaining liposomes with standardized plant extract 
    Stahi, Cristina; Yaman, Abdin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent years, scientists have shown an increasing interest in incorporating biologically active compounds extracted from plants into nanoparticle delivery systems. Examples of such delivery systems include ...
  • Anti-cancer compounds in brassica vegetables 
    Ciurea, Laura (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cancer is the main cause of mortality and morbidity worldwide. According to the World Cancer Research Fund an estimated 40% of all human cancers are related to diet. Although a large variety of therapeutic ...