USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3972
Title: Sinfluenţa compuşilor coordinativi ai cuprului asupra activităţii proteazelor lizozomale hepatice
Other Titles: Influence of the coordinative copper compounds on the activity of liver lisosomal proteases
Authors: Tagadiuc, Olga
Gudumac, Valentin
Andronache, Lilia
Rîvneac, Elena
Issue Date: 2010
Publisher: CEP Medicina
Citation: TAGADIUC, O., GUDUMAC, V., ANDRONACHE, L., RÎVNEAC, E. Sinfluenţa compuşilor coordinativi ai cuprului asupra activităţii proteazelor lizozomale hepatice. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 1: Probleme medico-biologice si farmaceutice, pp. 266-270. ISSN 1857-1719,
Abstract: The aim of the study was to investigate the influence of copper coordinative compounds CMT-28 and CMT-67 and their combinations with the cyanobacterial bioremedy BioR on the activity of lysosomal proteases in the liver of intact rats. It was established that all studied substances enhance the activity of cathepsines D, G, L, H, B and leucineaminopeptidase. CMT-67 and BioR show synergism in the modulation of the lysosomal proteases in the liver of intact animals, causing overlapping of the effects of these remedies.
Studiul a avut scopul de a cerceta influenţa compuşilor coordinativi ai cuprului CMT-28 şi CMT-67 şi a combinaţiilor lor cu remediul de origine cianobacterială BioR asupra activităţii proteazelor lizozomale în ficatul animalelor intacte. S-a stabilit că toate substanţele studiate amplifică activitatea catepsinelor D, G, L, H, B şi a leucinaminopeptidazei. CMT-67 şi BioR manifestă sinergism în modularea activităţii proteazelor lizozomale hepatice la animalele sănătoase, administrarea lor concomitentă determinînd cumularea efectelor acestor remedii.
URI: http://repository.usmf.md/handle/20.500.12710/3972
ISBN: 978-9975-113-45-8
ISSN: 1857-1719
Appears in Collections:Biochimie și genetică

Files in This Item:
File Description SizeFormat 
SINFLUENTA_COMPUSILOR_COORDINATIVI_AI_CUPRULUI.pdf277.46 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback