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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4729
Title: Studiul metabolismului şi analiza chimico-toxicologică a metaqualonei
Other Titles: Chemico-toxicological analysis of methaqualone
Authors: Marcova, Natalia
Rîşcovaia, Mariana
Cotelea, Tamara
Arama, Efim
Issue Date: 2012
Publisher: CEP "Medicina"
Citation: MARCOVA, Natalia, RÎŞCOVAIA, Mariana, COTELEA, Tamara, ARAMA, Efim. Studiul metabolismului şi analiza chimico-toxicologică a metaqualonei. In: Anale Științifice ale IP USMF “Nicolae Testemiţanu”. Ed. a 13-a. Chișinău: CEP Medicina, 2012, Vol. 1: Probleme medico-biologice şi farmaceutice, pp. 296-299.
Abstract: We elaborated the TLC method of methaqualone identification by using four developed systems, specrophotometric method of quantitative determination for methaqualone in tablets of 0.03g. Using the analytical methods elaborated by us over the artificial test there was extracted methaqualone from biological liquids (plasma, urine, saliva). The output of methaqualone from urine was 95.3%; Having considered the elaborated methods as specific and reproductive they are recommended for the study of methaqualone in biological liquids. A fost elaborată metoda cromatografiei pe strat subţire de identificare a metaqualonei, utilizând 4 sisteme de solvenţi,metoda spectrofotometrică de dozare în comrimate 0,03g, chromatografie de gaz. Aplicând metodele analitice elaborate de noi la probele biologice în „vitro” s-a efectuat extracţia metaqualoneiei din lichidele biologice. Randamentul metaqualonei din urină-95.3%. Dat fiind faptul, că metodele folosite sunt specifice şi reproductive ele se recomandă pentru studierea metaqualonei în lichidele biologice.
URI: http://repository.usmf.md/handle/20.500.12710/4729
Appears in Collections:Farmacie. Chimie generală

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