- IRMS - Nicolae Testemitanu SUMPh
- 1. COLECȚIA INSTITUȚIONALĂ
- Revista de Științe ale Sănătății din Moldova
- Revista de Științe ale Sănătății din Moldova : Moldovan Journal of Health Sciences 2024 Vol. 11, Issue 2
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/30047
Title: | Tetralogy of Fallot. Particularities in evolution according to the degree of severity of pulmonary stenosis |
Authors: | Kumaran, Durga Mohan Pîrțu, Lucia |
Keywords: | tetralogy of Fallot;pulmonary stenosis;evolution;outcomes;prognosis |
Issue Date: | 2024 |
Publisher: | Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova |
Citation: | KUMARAN, Durga Mohan; PÎRȚU, Lucia. Tetralogy of Fallot. Particularities in evolution according to the degree of severity of pulmonary stenosis. In: Revista de Ştiinţe ale Sănătăţii din Moldova = Moldovan Journal of Health Sciences. 2024, vol. 11, nr. 3, anexa 2, p. 667. ISSN 2345-1467. |
Abstract: | Background. Tetralogy of Fallot (TOF) is the most common
cyanotic congenital heart defect, representing about 10% of
all congenital heart defects which comprises four structural
defects: ventricular septal defect, pulmonary stenosis, overriding aorta, right ventricular hypertrophy. The degree of
severity of pulmonary stenosis hugely affects the patient’s
presentation, management and evolution. Objective of the
study. To analyze the particularities in evolution of TOF according to the degree of severity of pulmonary stenosis and
its significance on management and long-term follow ups.
Material and methods. Literature reviews on TOF according to mild, moderate and severe degree of pulmonary stenosis were bought into study and its management measures
based on clinical data, paraclinical investigations and outcomes were recorded. The evolution, course, and prognosis
of the classified groups was determined through analysis.
Results. Evaluation of pulmonary stenosis using echocardiography had been done for increased visualization of the pulmonic valve. Most patients with mild pulmonary
stenosis are asymptomatic, moderate or severe patients
who experience dyspnea on exertion or associated fatigue,
depending on the severity of the obstruction. Infants with
critical pulmonary stenosis presented with cyanosis after
birth. Studies show that patients with mild or moderate stenosis had better outcomes and less mortality than severe
stenosis which have poor outcomes and higher mortality.
The less severe stenosis is well tolerated than severe stenosis in neonatal ductal dependent stenosis. Conclusion.
Catheter-based therapy is corrective for the majority of patients with isolated valvular pulmonary stenosis and surgical therapy in patients with subvalvular and supravalvular
obstruction and use of a catheter-based intervention during
continued follow-up and surveillance of these patients. |
metadata.dc.relation.ispartof: | Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences |
URI: | https://cercetare.usmf.md/sites/default/files/inline-files/MJHS_11_3_2024_anexa2__site.pdf http://repository.usmf.md/handle/20.500.12710/30047 |
ISSN: | 2345-1467 |
Appears in Collections: | Revista de Științe ale Sănătății din Moldova : Moldovan Journal of Health Sciences 2024 Vol. 11, Issue 2
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