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- IRMS - Nicolae Testemitanu SUMPh
- 1. COLECȚIA INSTITUȚIONALĂ
- Revista de Științe ale Sănătății din Moldova
- Revista de Științe ale Sănătății din Moldova : Moldovan Journal of Health Sciences 2026 Vol. 13, Issue 3
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/33742
| Title: | Elective versus emergency umbilical hernia repair in patients with decompensated cirrhosis: a retrospective cohort study |
| Authors: | Pisarenco, Sergiu Anghelici, Gheorghe Zugrav, Tatiana Crudu, Oleg Lupu, Gheorghe Chiriac, Liviu |
| Keywords: | liver cirrhosis;ascites;umbilical hernia;elective surgical procedures;emergency treatment;postoperative complications |
| Issue Date: | 2026 |
| Publisher: | Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova |
| Citation: | PISARENCO, Sergiu; Gheorghe ANGHELICI; Tatiana ZUGRAV; Oleg CRUDU; Gheorghe LUPU and Liviu CHIRIAC. Elective versus emergency umbilical hernia repair in patients with decompensated cirrhosis: a retrospective cohort study. Revista de Ştiinţe ale Sănătăţii din Moldova = Moldovan Journal of Health Sciences. 2026, vol. 13, nr. 3, pp. 27-35. ISSN 2345-1467. https://doi.org/10.52645/MJHS.2026.3.04 |
| Abstract: | Introduction. Evidence on umbilical hernia repair in patients with decompensated cirrhosis, ascites, and Child–Pugh class
C is limited. In this population, outcomes after emergency repair may reflect both the urgency of the presentation and the
greater hepatic, renal, inflammatory, and metabolic derangement present at the time of surgery.
Materials and methods. This retrospective single-center cohort study included all 40 eligible adults with decompensated cirrhosis, ascites, and Child–Pugh class C at admission who underwent open primary non-mesh umbilical hernia
repair between January 2019 and December 2025. Twenty patients underwent elective repair, defined as definitive repair
scheduled after a short period of inpatient optimization, and 20 underwent emergency repair after limited stabilization because an acute hernia-related indication made postponement unsafe. The primary outcome was all-cause 30-day mortality.
Secondary outcomes were in-hospital mortality, acute kidney injury, sepsis, wound infection, persistent ascitic leakage,
reoperation, length of hospital stay, and early postoperative clinical-biochemical status. Analyses were unadjusted and
exploratory; no multivariable model was fitted.
Results. At admission, the emergency group had higher total bilirubin, international normalized ratio, creatinine, leukocyte count, Child–Pugh score and MELD-Na score, and lower serum albumin and sodium (all p ≤ 0.006). During a median
elective optimization interval of 4.5 (3.0–6.0) days, the MELD-Na score decreased by a median of 2 (1–3) points. On postoperative days 2–3, every reported clinical-biochemical indicator remained less favorable in the emergency group. Median
hospital stay was 14.5 versus 11.0 days (p = 0.038). Thirty-day mortality was 35.0% versus 10.0% (risk difference 25.0%,
95% confidence interval −1.3 to 47.9; p = 0.127).
Conclusions. Patients undergoing emergency repair reached surgery with substantially greater clinical and biochemical
derangement, had a less favorable early postoperative profile and stayed longer in the hospital, while the mortality difference did not reach statistical significance. Because operative timing was determined by the clinical course, the groups were
not comparable at baseline and no causal effect of urgency or of preoperative optimization can be inferred. The findings
support early multidisciplinary assessment while an elective operative pathway remains feasible. |
| metadata.dc.relation.ispartof: | Revista de Științe ale Sănătății din Moldova = Moldovan Journal of Health Sciences |
| URI: | https://doi.org/10.52645/MJHS.2026.3.04 https://mjhs.md/api/media-documents/file/MJHS_13_3_2026_red.pdf https://repository.usmf.md/handle/20.500.12710/33742 |
| ISSN: | 2345-1467 |
| Appears in Collections: | Revista de Științe ale Sănătății din Moldova : Moldovan Journal of Health Sciences 2026 Vol. 13, Issue 3
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