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Actual diagnostic methods used in nontuberculous mycobacteria infections

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dc.contributor.author Ciobanu, Victoria
dc.date.accessioned 2020-07-03T06:28:02Z
dc.date.available 2020-07-03T06:28:02Z
dc.date.issued 2018
dc.identifier.citation CIOBANU, Victoria. Actual diagnostic methods used in nontuberculous mycobacteria infections. In: MedEspera: the 7th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2018, p. 195-196. en_US
dc.identifier.uri https://medespera.asr.md/wp-content/uploads/Abastract-Book-2018.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/10875
dc.description Department of Mycrobiology and Imunology, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova en_US
dc.description.abstract Introduction. Nontuberculous mycobateria, also called atypical mycobacteria, for a long period of time, were considered to be inoffensive for humans. Nowadays they are considered to be very wide spread and responsible for many atypical clinical manifestations such as localized lymphadenitis, tuberculosis like extrapulmonar lesions, disseminated form and so on. There a known more species today than 30 years ago, and all of them are classified in Ernest Runyon classification which dates from 1959.It includes four groups of atypical mycobacteria in dependence of coloration and rapidity of growth: group I-photochromogens; group II-cotochromogens; group III-nonchromogens; group IV-rapid growing. These mycobacteria live in water, air and soil, that’s why they can contaminate organisms throughout airflow, via parenteral and enteral way. The diagnosis is not so hard, but in many cases irrelevant because of the possibility of atypical mycobacteria to contaminate containers for sputum collection. Aim of the study. To analyse the actual situation of atypical mycobacteria diagnosis in our country, the diagnostic methods used for confirmation here and abroad. Materials and methods. The diagnosis of nontuberculuos mycobacteria is based on 3 criteria: 1) Clinical criterion: cough, fever, dyspnea and fatigue; 2) Radiologic criterion: persistent nodular infiltration; 3) Microbiologic criterion: positive culture and positive microscopic view. Each positive culture is the confirmed via GenoType® Mycobacterium CM test. 201 cases of nontuberculous mycobacteria infections were confirmed in 2015-2017 in Republic of Moldova. All of them were confirmed from sputum. Results. Most of the cases could be found in presenile patiens, mostly in women and high incidence of species m. fortuitum followed by m. kansasii is revealed Conclusions. The only method of diagnosis available at this moment in our country and abroad ,to confirm the atypical mycobacteria infection was GenoType® Mycobacterium CM test. Most of the cases could be found in presenile patiens, almost in women. A high incidence of species m.fortuitum followed by m.kansasii was found in our country which leads to the most common transmition way of non-tuberculous mycbacteria. en_US
dc.language.iso en en_US
dc.publisher MedEspera en_US
dc.subject nontuberculous mycobacteria en_US
dc.subject clinical manifestations en_US
dc.subject diagnostic criteria en_US
dc.title Actual diagnostic methods used in nontuberculous mycobacteria infections en_US
dc.type Article en_US


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  • MedEspera 2018
    The 7th International Medical Congress for Students and Young Doctors, May 3-5, 2018

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