The thromboembolic risk at the patients with non valvular trial fibrillation

Abstract

Introduction. Atrial fibrilation is the most common cardiac arhytmia and is Associated with a substantial risk of stroke and mortality.The prevalence of atrial fibrillation is related to age and is projected to rise exponentially as the population ages and the prevalence of cardiovascular risk factors increases. The risk of ischemic stroke is significantly increased at atrial fibrillation patients, and there is evidence of increased risk of stroke Associated with advancing age. The objective of the study is the determination of thromboembolic risk at the patients with non-valvular fibrillation with the CHA2DS2VASc. Materials and methodes. This study was conducted on 110 patients (aged 47 and 83 years old) with non-valvular atrial fibrillation, hospitalized in MCH,,Holy Trinity’’ during october 2014- march 2016. The study was made on 65 females(59,09%) and 45 males(40,91%).The factors that could influence the thromboembolic risk were analyzed. Were utilized the next tests: CHA2DS2VASc score and HAS-BLED score. Laboratory analysis: Total Cholesterol; HDL- cholesterol; Triglycerides; Glycemie; Body mass index. Results. Pacients with age less than 65 years: 11(10%-males:4,5% and females:5,5%); 65-75 years: 70(63,63%- males: 28,2% and females 35,5%); older than 75 years: 29(26,36% -males:8,18% and females:18,18%). At the patients with the following risk factors were identified: the low thromboembolic risk-0%; moderate – 2,73%; high – 97,2%. The predominant risk factors: arterial hypertension- 93,63%(103); diabetes mellitus-24,6% (27); vascular disease( MI, PAD)-15,45% (17); stroke/TiA or thromboembolism-10,91% (12).Conclusion. The prevalence of atrial fibrillation increases markedly with older age: about 5% of people over 65 years and 10% of people age older than 80 years suffer from atrial fibrillation.The CHA2DS2VASc score can help estimate stroke risk in patients with non-valvular atrial fibrillation and determine which antithrombotic therapy ist most appropriate.