Abstract:
Introduction. Some oral mucosal diseases appear as a result of immunodeficiency of the
organism caused by systemic diseases. In recent years, it has been shown that chronic hepatitis B
and C infection, in addition to causing liver disease, is also responsible for several extrahepatic
manifestations and immune abnormalities. Chronic viral hepatitis B and C was found to be
involved in the pathogenesis of some oral diseases. The diagnostic process includes some
sequential steps to elucidate the cause itself and to provide an adequate plan of treatment.
Aim of the study. To provide general aspects in diagnosis of oral mucosal diseases of the
patients with chronic viral hepatitis B and C using the review from literature.
Materials and methods. The dates found in five scientific articles from different countries were
selected in this study. An overview from literature on the diagnosis data of the oral mucosal
diseases of the patients with chronic viral hepatitis B and C was done.
Results. The analyzis of the methods used to diagnose the oral mucosal diseases revealed the
important role of knowing their etiology on establishing the correct treatment plan. Besides the
clinical diagnostic, a big importance in diagnosis has the paraclinical examination, which
includes: biopsy of the affected tissues, microbiological tests, radiological examinations,
immunofluorescence tests. In addition to these examinations, the tests for chronic viral hepatitis
B and C have to be done, such as: serologic examination (hepatic markers), molecular-biological
and immunologic testes.
Conclusions. According to the five scientific articles, the diagnosis of oral mucosal diseases of
the patients with chronic viral hepatitis B and C involves four sequential steps: 1. obtaining of
comprehensive overview of the patient’s local and general status; 2. evaluation of all the findings
to correlate the chief sight of symptoms with the current history, 3. physical findings and medical
history; 4. establishment of differential diagnosis.
