Abstract:
Introduction. Statins are a class of lipid-lowering medications, also known as HMG-CoA
reductase inhibitors. They are considered one of the most popular prescribed agents worldwide
for treatment of hypercholesterolemia. Statins are effective drugs to reduce cardiovascular events and mortality secondary to dyslipidemia. Statin therapy is considered as the standard
dyslipidemia therapy. Except lipid-lowering effect, it is known that statins have cholesterolindependent
effects (pleiotropic effects).