Results of the study of intestine biocenosis in children

Abstract

Introduction. Changes in intestinal microbiocenosis play an important role in the development of functional disorders of the digestive tract in children. The aim of the study was to determine the diagnostic value of bacteriological studies of intestinal dysbiosis. Patients and methods. We performed a retrospective analysis of 127 results of fecal survey on dysbiosis in children aged 1 to 17 years with impaired bowel function, that turned to the Odessa Regional Children's Clinical Hospital in 2014-2015. Results. According to our research, more of the analysis on dysbiosis was conducted in patients of younger age group of 1 to 3 years ─ 68,8% of all cases. In the same age group, 81.4% examinationed children were bacteriological signs of dysbiosis of transient nature. There was a seasonal correlation of the research, since 44.8% of analyzes were carried out in the period from February to April, due to an increase in functional disorders of the digestive tract in children during this period. For the majority ofpatients (78.6%) fecal dysbiosis has been performed in occasion of functional disorders of the gastrointestinal tract. The most common conditional pathogens St. Aureus were detected in the youngest age groups: from 1 year up to 3 years ─ at 44.2%; 4 to 7 years old children ─ 42,3%. On the second place were sown fungi of the genus Candida and other yeast in 38.6% of patients, as well mainly in young children. On the third place - E.cloaceae (11,02%) and lactosonegative (10,8%) Escherichia, then Kl. Pneumoniae 9,4%, P.aeruginosa in 2.36% of patients, respectively. The remaining microorganisms disembarked in single cases. Results of analyzes, unfortunately, were ready on day 10, when was advanced clinical remission in patients and there was no need for a correction of infringements. Conclusions. Violation of intestinal microbiocenosis is most characteristic for young children, is rarely correlated with clinical data and is transient. Are most commonly defined conditional Pathogens St.Aureus and fungi of the genus Candida. However, the diagnostic value of the study is reduced due to the timing of the tests.