Abstract:
Introduction. Parkinson's disease (PD) is one of the major progressive neurological disorders
for which preventative or long-term treatment strategies are not available. Despite intense
research over the last decade, PD etiology is still not completely understood. PD appears to stem
from the result of complex gene interactions with environmental factors. The most common risk
factors for the development of PD are the use of pesticides, traumatic brain injury, the rural
environment, and the use of coffee and smoking are considered as protective factors.