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Screening the C677T polymorphism of the MTHFR gene in assessing disease severity and response to methotrexate treatment in children with juvenile idiopathic arthritis

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dc.contributor.author Iacomi, Vladimir
dc.date.accessioned 2020-07-07T14:11:23Z
dc.date.available 2020-07-07T14:11:23Z
dc.date.issued 2018
dc.identifier.citation IACOMI, Vladimir. Screening the C677T polymorphism of the MTHFR gene in assessing disease severity and response to methotrexate treatment in children with juvenile idiopathic arthritis. In: MedEspera: the 7th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2018, p. 62-63. en_US
dc.identifier.uri https://medespera.asr.md/wp-content/uploads/Abastract-Book-2018.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/11106
dc.description Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova, Pediatric Rheumatology Unit, Scientific Research Institute for Mother and Child Health Care of the Republic of Moldova en_US
dc.description.abstract Introduction. Existing data regarding the association of the mutation of methylenetetrahydrofolate reductase (MTHFR) gene with methotrexate (MTX) treatment efficacy and side effects in patients with juvenile idiopathic arthritis (JIA) is still contradictory. Therefore, genetic studies of the role of this mutation are necessary in order to provide personalized treatment for this group of patients and decrease the risk of MTX side effects. en_US
dc.language.iso en en_US
dc.publisher MedEspera en_US
dc.subject methylenetetrahydrofolate reductase en_US
dc.subject methotrexate en_US
dc.subject arthritis en_US
dc.subject children en_US
dc.title Screening the C677T polymorphism of the MTHFR gene in assessing disease severity and response to methotrexate treatment in children with juvenile idiopathic arthritis en_US
dc.type Article en_US


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  • MedEspera 2018
    The 7th International Medical Congress for Students and Young Doctors, May 3-5, 2018

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