Analysis of nano drugs

Abstract

Introduction. The properties of drug substances incorporated into nano-systems are often due not only to the properties of the substance but also to the nano-systems of which they are part. For this reason, the assessment of the quality of a nano drug requires a more complex check, which involves checking the structure of the nanoparticle. In particular, a rigorous control of their size is indispensable to ensure the improvement of the pharmacokinetic and pharmacodynamic behavior of the active substances. To meet these requirements, nano-drug analysis methods are supposed to be applied. Aim of the study. Study of nano-drug analysis methods. Materials and methods. The review of scientific literature on nanomedicine analysis methods has been performed. Results. Information from literature demonstrates a number of advantages of using nano-drugs. The transport of the drug is directly to the biological target, bypassing the adverse effects and maximizing the therapeutic effect. For a uniform distribution of dispersion sizes it is useful to use the calibration technique. An important reason is that nano-size offers a number of advantages such as: significant increase in total particle size, increased solubility, bioavailability and drug dose reduction. Conclusions. The progress of nanotechnologies and the development of different types of nanoparticles offer new opportunities and challenges for medicine and pharmacy. So the traditional methods of existing analysis that are applied in this area are not enough when it comes to nanomedicines. However, fortunately, technological progress has brought new, more sophisticated analysis technologies that open up new opportunities in nanomedicine research.