Abstract:
Introduction. Premature rupture of membranes (PROM) refers to rupture of the fetal
membranes prior to the onset of labor irrespective of gestation age. PROM represents a serious
problem of modern obstetrics. In 25-38% of cases premature birth is preceded by PROM, which
contributes to the increase of perinatal morbidity and mortality in 30% of cases. One of the most
difficult issues in the management of a pregnancy with PROM is the correlation between the risk
infection in the case of prolonged pregnancy and the risk of prematurity due to delivery.
