The Moldovan Medical Journal: Recent submissions

  • Inoffensivity of imupurin in pregnancy 
    Pogonea, Ina; Catcov, Carolina; Ghicavîi, Victor (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Determination of imupurin inoffensivity on embryogenesis, organogenesis and teratogenesis in rats. Material and methods: The study of immupurin’s safety during pregnancy was performed on 60 rats, divided into ...
  • Tumor associated macrophages in breast cancer 
    Carpenco, Ecaterina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cancer research was focused on the studying of proper tumor cells for a long time. Despite the huge progress, there are still a lot of questions, that’s why new molecular markers must be identified. These could ...
  • Tuberculosis characteristics and risk factors in urban compared with rural patients 
    Tihon, Aliona; Tafuni, Ovidiu; Malik, Alina; Niguleanu, Radu; Osipov, Tatiana; Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Material and methods: A retrospective selective, descriptive study of socioeconomic, epidemiological peculiarities, case-management, diagnosis and microbiological characteristics of 694 patients with tuberculosis registered ...
  • Hepatocytes isolation from adult rats for liver recellularization 
    Jian, Mariana; Cobzac, Vitalie; Vartic, Victoria; Nacu, Viorel (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Currently hepatocytes obtaining is prerequisite to create the necessary conditions for medical research, because it is an important tool in developing of new strategies in tissue engineering domain, which ...
  • The stable-functional osteosynthesis of clavicular fractures with external fixator 
    Roșu, Gheorghe (The Scientific Medical Association of the Republic of Moldova, 2019-03)
    Background: Over the past two decades has been paid insufficient attention to the treatment of patients with clavicle fractures. Analysis is of the recent available literature and the personal practice allow us to have a ...
  • Level of cytokines in patients with pulmonary drug susceptible and resistant tuberculosis 
    Lesnic, Evelina (The Scientific Medical Association of the Republic of Moldova, 2019)
    Background: Cytokines are the regulators of the immune response in tuberculosis: TNF-alpha and CXCL8 (IL-8) are involved in the granuloma formation, IL-10 inhibits the inflammation; some chemokines increase the liver ...
  • Surveillance of antimicrobials use in Emergency Medicine Institute 
    Bernaz, Emilian P.; Ciobanu, Gheorghe Ch.; Tentiuc, Elizaveta V.; Borovic, Eduard I.; Vovc, Liviu A. (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Antibiotics have had a profound impact on humanity’s health, by improving our ability to prevent, cure and reduce the transmission of many infectious diseases. It is widely known, that the unnecessary or ...
  • Experimental study of new 3-(2-R1 -6-R2 -4-oxyquinoline-3(4H)-yl)alkyl (alkaryl-, aryl) carboxylic acid derivative (PC-66 compound) 
    Kramar, Hanna (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Screening studies have revealed in new 3-(2-R1-6-R2-4-oxyquinoline-3(4H)-yl)alkyl (alkaryl-, aryl) carboxylic acid derivative (PC-66 compound) expressive analgesic properties without any damaging effects on ...
  • Antimicrobial effect of biodegradable wound healing nano-containing polymer materials 
    Popadyuk, Oleh Yaroslavovytch (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Treatment of infected wounds presents the biggest difficulty for the surgeon. The treatment of skin lesions has recently increased due to the effect of developed local multi-application forms saturated with ...
  • Infravesical urinary tract obstruction and transurethral endoscopic approach of treatment 
    Ghicavii, Vitalii (The Scientific Medical Association of the Republic of Moldova, 2017)
    Backqround: The results of scientifical progress in recent years have contributed to the development of transurethral endoscopic surgery, with the implementation of new methods, less invasive, for the treatment of the ...
  • Argumentation of the strategic directions for the development of pharmaceutical system in the Republic of Moldova 
    Adauji, Stela; Buliga, Valentina; Safta, Vladimir; Brumarel, Mihail; Lupu, Mihail; Spinei, Larisa (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: To assess the actual pharmaceutical system in Moldova in order to show the strategic directions of the development of this system. Material and methods: The methodology of the study is based on the systemic ...
  • B-cell lymphoma-2 receptor in human primary breast and its lymph node metastases: more than a surrogate marker 
    Fulga, Veaceslav; Ceausu, Amalia Raluca; Cimpean, Anca Maria; Saptefrati, Lilian; Raica, Marius (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Due to its anti-apoptotic and anti-proliferative contradictory functions, BCL2 role in breast carcinoma progression is not clearly understood. The purpose of this study was to highlight BCL2 expression during ...
  • Homocysteine and recurrent miscarriage 
    Visternicean, Elena (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: It is known that etiological structure of recurrent miscarriage has genetic, anatomical, infectious and immunological factors; however, the cause of recurrent miscarriage in 50-60% of cases is not completely ...
  • Metabolic syndrome as a risk factor for ischemic stroke 
    Ciobanu, Natalia; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Ischemic stroke is the leading cause of disability and a major cause of mortality worldwide. It is predominantly seen in the elderly and in patients with the metabolic syndrome (MS) [1, 2]. Material and ...
  • Markers of apoptosis and oxidative stress in congestive heart failure 
    Mamadova, Farah; Azizova, Gulnara; Dadashova, Arzu (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: The aim of this work is to study the markers of apoptosis (granzyme B) and oxidative stress (nitric oxide), as well as indicators of endothelial damage - cystatin C and lipid metabolism in patients with ...
  • Analysis of the legislation of the Republic of Moldova in terms of pharmaceutical security 
    Buliga, Valentina (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: The pharmaceutical security can only be ensured taking into account its multidimensional and systemic character; the partial or one-sided approach will not ensure the feasibility and the sustainability of such ...
  • Radiofrequency ablation – new insights into the modern treatment of atrial flutter and fibrillation 
    Grib, Liviu; Cenusa, Octavian; Varvariuc, Viorica; Abraș, Marcel; Grib, Andrei; Grajdieru, Romeo (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Atrial fibrillation (AF) is associated with a 5-fold increase in the risk of stroke and a 3-fold increase in the incidence of heart failure. The increase in AF prevalence can be attributed both to better ...
  • Intrauterine growth restriction: contemporary issues in diagnosis and management 
    Capros, Hristiana; Scoricova, Iana; Mihalcean, Luminita (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Intrauterine growth restriction represents a fetal life treating condition in obstetrics. Diagnosis and appropriate management during pregnancy is essential because of the considerable morbidity and mortality ...
  • Infrared thermographic evaluation of patients with metastatic vertebral fractures after combined minimal invasive surgical treatment 
    Olaru, Andrei (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: Vertebral cement augmentation and external beam radiotherapy have become increasingly used techniques for treatment of vertebral compression fractures due to spinal metastatic lesions in the Republic of Moldova. ...
  • Cranial deformities as a risk factor in the harmonious development of oral and maxillofacial region 
    Railean, Silvia (The Scientific Medical Association of the Republic of Moldova, 2017)
    Background: There is no information about cranio-facial asymmetry among school children and the influence of this pathology on the quality of life. Material and methods: The study presents a descriptive analysis of 3923 ...

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