Biomarkers in ovarian cancer

Abstract

Introduction: Elucidation of the most frequent biomarkers in ovarian cancer. Materials and methods: The study was based on the analysis of biographical sources from 2007- 2014.

Discussion results: One of the major challenges in cancer research is the identification of stable biomarkers, which can be routinely measured noninvasively in easily accessible samples. Ovarian cancer is one such disease that would benefit from improved diagnostic markers. Ovarian cancer is the leading cause of death from gynecological malignancy in the western world. One way to facilitate early detection of ovarian cancer is through screening, but currently available diagnostic tools, including ovarian cancer biomarkers and clinical imaging, lack sufficient specificity and sensitivity for implementation in a population-based screening program.

Conclusions: The ability to sensitively and specifically predict the presence of early disease and its status, stage and Associated therapeutic efficacy has the potential to revolutionize ovarian cancer detection and treatment and to greatly improve the quality of life and survival rates of ovarian cancer patients.