Standardized foam for sclerotherapy of varicose veins of lower limbs: is it better?

Abstract

Introduction: Nowadays the foam scleroterapy is becoming the top choice of the majority of vascular surgeons for varicose disease treatment, altough a standartized method of producing SF has not been chosen yet. Aims: To appreciate the difference between the half-life of the sclerosant foam (SF) obtained by using different types of syringes connected by a two-way connector, and the one obtained by using the Kreussler Pharma Easy Foam Kit. Methods: In CCGS labaratory of USMF,,Nicolae Testemitanu” an experimental study was performed. By using Trombovar 3% and Etoxisclerol 3%, together with room air, different brands and volumes of syringes, siliconized and unsiliconized syringes, a two-way connector and Kreussler Pharma Easy Foam Kit, SF was obtained. The liquid-to-gas ratio was 1:4, with 20 passages. Results: The SF hal-life varried unsignifically when using both Trombovar 3% and Etoxisclerol 3%, as well as using Kreussler Pharma Easy Foam Kit did not increase the SF half-life, compared to the syringes connected by a two-way connector. The volume of the syringes used in the experimental study, had no influence on the SF half-life. However, the unsyliconized syringes seem to potentiate the durability of the SF. Conclusion: SF formation is greatly influenced by the choice of the types of syringes, also unsiliconized syringes are to be preferred for obtaining of SF.