Abstract:
Background. Sarcomas are malignant tumors of mesenchymal origin, constituting 1-2% of all solid
tumors. Their prognosis is reserved with a 5-year survival rate of 36-58%, and the recurrence rate being
50-60%. The basic treatment for TRP is surgery. Objective of the study. The assessment of clinical and
paraclinical particularities of retroperitoneal sarcomas, as well as the methods of treatment and its
prognosis. Material and Methods. Collected data from scientific specialty literature, that were found
in Google Scholar Search, and from published studies on PubMed, Scopus, International practice clinic
guidlines. The including criteria was the articles that contained the topic of “Retroperitoneal
tumors”. Results. Were analyzed 38 articles in the period of 2019-2020 that contained the topic of
“Retroperitoneal sarcomas”. SRP were localized in 76% of patients in the retroperitoneal perirenal
space. The most frequent histological type was liposarcoma, and leiomyosarcoma was found only in 5-
10% of cases. The CT scan has a rate of diagnostic accuracy of 97% in the case of TRP.Usually
intraoperative the sarcoma is seen with an irregular contour, being of a high density and affecting the
surrounding tissue and neighbor organs. The recurrence rate after combined surgical treatment and
chemotherapy or radiotherapy is usually of 14%. Conclusion. Liposarcoma and leiomyosarcoma found
only in 5-10% of cases. The CT scan is the gold standard of diagnostics, the 5-year survival rate is of
36-58%, found usually after a surgical, chemotherapy or radiotherapy treatment, with a relapse rate of
50-60%.
Introducere: Sarcoamele sunt tumori maligne cu origine mezenchimală, constituind 1-2% din toate
tumorile solide. Prognosticul acestora este rezervat, speranța de viață la 5 ani fiind de 36-58%. Deși rar
metastazează, rata recidivelor este de 50-60%. Tratamentul de bază al TRP este chirurgical. Scopul
lucrării. Evaluarea particularităţilor clinice, paraclinice ale tratamentului şi prognosticul sarcoamelor
retroperitoneale. Material și Metode. S-au studiat datele literaturii științifice de specialitate, identificate
de motorul de căutare Google Search și din bazele de date PubMed, Scopus, Protocoale clinice
internaționale. Criteriile de includere a articolelor au fost „tumorile retroperitoneale”. Rezultate. Au
fost procesate 38 de articole, anii 2019-2020 privind sarcoamele retroperitoneale. SRP la 76% pacienţi
au avut localizare în spațiul retroperitoneal perirenal. Cea mai frecventă formă histologică este
liposarcomul, iar leiomiosarcomul fiind cea mai rară de 5-10%. Tomografia computerizată are o rată de
precizie de 97% a TRP; intraoperator au contur neregulat, consistenţă densă cu implicarea ţesuturilor şi
organelor adiacente. Rata de recidivă după tratamentul chirurgical este de 50%-
60%. Concluzii. Liposarcomul este cea mai frecventă formă histologică, iar leiomiosarcomul fiind cea
mai rară de 5-10%. CT este standartul de aur de diagnostic, iar tratamentul chirurgical, chimioterapic
sau radioterapic oferă o rată de supravieţuire la 5 ani de 36-58%, rata recidivării fiind de 50-60%.
