Summary. The importance and necessity of the present study was
imposed by the fact that a standard antiviral treatment
was not elaborated in case of acute viral hepatitis C
(AVHC). Taking into account the large percentage
of chronicity of hepatitis with virus C, the treatment
itself should be an antiviral one. To establish the effi ciency of combined antiviral treatment with pegasys
and copegus, 40 patients with AVHC participated
in the study, 12 of which were females (30%) and
28 males (70%) of average age 43,54 ±1,68 years
old. To confi rm the diagnosis anamnesis, clinical,
epidemiological and laboratory data have been
analized. The haemoleucogram, biochemical tests of
the liver (bilirubin, ALAT, thymol test, prothrombin),
the markers of the viral C hepatitis (anti-VHC IgM,
anti-VHC tot9) were investigated by excluding other
viral hepatites (by determining the viral B and D
hepatites markers), the abdominal ecography and the
ARN-VHC by PCR. A combined antiviral treatment
was initiated with pegasys+copegus. The clinical
symptomatology of the patients in the study was
demonstrated by symptoms of dispeptic asthenic and
arthralgic symptoms. The contamination occured
mainly paranterally. The treatment with pegasys
+ copegus was effi cient (SVR – 100%) and can be
recommended for acute forms of hepatitis C.
Резюме. Актуальность проводимых исследований состоит в том, что до сих пор не разработан
стандарт противовирусного лечения острого
вирусного гепатита С (ОВТС).
Под наблюдением находились 40 больных с ОВГС
– 12 женщин и 28 мужчин, у которых диагноз
установлен на основании биохимических, серологических и молекулярно-биологических методов
исследования. Было назначено комбинированное
лечение пегасисом и копегусом. Пегасис – 180 мкг
в неделю в.м. а копегус – в дозе 1000 – 1200 мг в
день, в зависимости от веса.
Длительность лечения – от 12, 24 и 48 недель.
Лечение пегасисом и копегусом было эффективным и привело к 100% выздоровлению и может
быть рекомендовано для лечения острых форм
гепатита С.
