A polyphenolic extract and one polyholosidic from of aerial parts of Cyani herba were made at the Department of Pharmacognosy of
SUMPh “Nicolae Testemiţanu”. The aim of the study was: Determination of acute toxicity of polyphenols and polysaccharides extract of
Cyani herba. The obtained results shows that enteral LD0 for both extracts (the minimal administrated dose) was 4000 mg/kg at enteral
administration, LD 25%, LD 50%, and LD 100% haven’t been established. The obtained LD value classifies the studied plant extracts
as slightly toxic. The results suggest that the polyphenols and polysaccharides extracts of the aerial parts of Centaurea cyanus L. are
relatively safe toxicologically.
Rezumat. În cadrul Catedrei Farmacognozie a USMF ”Nicolae Testemiţanu” a fost realizat un extract polifenolic şi unul poliholozidic
din părţi aeriene de albăstriţă Cyani herba. Scopul studiului a constituit: Determinarea toxicităţii acute a extractului polifenolic şi poliholozidic
din Cyani herba. Rezultatele obtinute ne-a permis sa stabilim ca LD0 pentru ambele extracte din Ch a constituit 4000 mg/kg
(doza maxim administrata) la administrare enterala, dozele LD 25%, LD 50%, LD 100% nefiind stabilite. Constatam toxicitatea minimă
extractelor polifenolic şi poliholozidic din părţi aeriene de albăstriţă Cyani herba.
