Abstract:
Pre-immune resistance is the most ancient type
of defense that appeared before the acquired immunity.
Numerous observations showed that immunity (immunological reactivity) begins its fight with infection no
earlier than 7-8 days from the moment of the microbe
penetration into the body. During this time, microbes do
not multiply freely in the body. They are resisted by biological mechanisms of pre-immune protection against
infections (integumentary tissues, vascular reactions,
bactericidal and bacteria bindinghumoral components
of secretions and serum, phagocytes). Consequently,
the cell carriers of the pre-immune defense against infections and their soluble products recognize the fact
of penetration of the pathogen into the body first, long
before the immune cells.
Description:
Department of Otolaryngology, Nicolae Testemitanu State University of Medicine and Pharmacy, Laboratory of Immunology and Allergology of the Institute of Phthisiopneumology
Chiril Draganiuc, Chisinau, Moldova
