Abstract:
Introduction. Airway inflammation is a common feature of many diseases. Its repercussions can be discovered in
many aspects of the disease, therefore finding the biomarker or combination of biomarkers to define it continues to
be challenging.
The scientific material and methods used are the review of current literature data, controversies, discordances and
peculiarities of respiratory tract inflammation and biomarkers capable to assess it.
The results are centered on those biomarkers capable to capture inflammation from as many angles as possible, with
impact not only on the pathogenesis of the disease but also with clinical, evolution, therapeutic and monitoring implications.
Conclusions. For airway inflammation many biomarkers are useful, some define the disease as a whole, some are
defining for certain aspects or endotypes. The winning combination proposed by many authors appears to be a panel
of biomarkers which captures as many aspects as possible for each entity, but is usually difficult to find.
Description:
Universitatea Lucian Blaga Sibiu, Facultatea de Medicină,
Spitalul Clinic de Pediatrie Sibiu,
Centrul de Cercetări şi Telemedicină în Bolile Neurologice la copil,
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Departamentul Pediatrie
