Institutional Repository in Medical Sciences
(IRMS – Nicolae Testemițanu SUMPh)

Browsing The Moldovan Medical Journal, Vol. 64, No 3, September 2021 by Issue Date

Browsing The Moldovan Medical Journal, Vol. 64, No 3, September 2021 by Issue Date

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  • Co-occurrence of voltage-gated calcium channel and acetylcholine receptor antibodies: case report 
    Bubuioc, Ana-Maria; Cernei, Irina; Gheceva, Oxana; Gavriliuc, Mihail; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Voltage-gated calcium channels (VGCC) antibodies are generally associated with Lambert Eaton myasthenic syndrome (LEMS). Their coexistence with acetylcholine receptor (AchR) antibodies, which are specific for ...
  • Familial epilepsy – clinical-epidemiological characteristics and next-generation sequencing in the Republic of Moldova’s population 
    Gasnas, Daniela; Chelban, Viorica; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Although several theories are implicated in the origin of epilepsy, its cause is still unknown in about 50% of cases. To associate a gene with epilepsy for the first time, families with multiple affected members ...
  • Treatment of acute ischemic stroke by systemic thrombolysis combined with endovascular thrombectomy: case report 
    Condrea, Alexandra; Zota, Eremei; Crivorucica, Igor; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: A small number of acute ischemic stroke (AIS) patients meets eligibility criteria for systemic thrombolysis (ST) with recombinant tissue plasminogen activator, but its efficacy for large vessel occlusion is ...
  • Management of brain tumor-related epilepsy: case report 
    Condrea, Alexandra; Aftene, Daniela; Chiosa, Vitalie; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Patients with brain tumor related epilepsy present a complex therapeutic profile and require a unique and multidisciplinary approach. Difficulty in managing epilepsy in patients with brain tumors stems from ...
  • Efficacy of implementation of the FeSS protocol in thrombolysed stroke patients from Institute of Emergency Medicine 
    Zota, Eremei; Crivorucica, Igor; Belitei, Doina; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Implementation of intravenous thrombolysis for acute ischemic stroke has significant impact on stroke outcome by reducing disability and post-stroke mortality rates. However, high risk for developing early ...
  • Update on current knowledge on poststroke epilepsy 
    Cucusciuc, Cristina; Gasnas, Alexandru; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The main cause of seizures in adults beyond the age of 60s is represented by cerebrovascular diseases, mainly hemorrhagic and ischemic strokes. Poststroke epilepsy (PSE) is one of their complications, that ...
  • Role of nutritional and lifestyle factors on the Amyotrophic Lateral Sclerosis progression. Results from a multicenter cross-sectional study 
    Cucovici, Aliona; Ivashynka, Andrei; Fontana, Andrea; Lisnic, Vitalie; Leone, Maurizio A. (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Amyotrophic Lateral Sclerosis is a devastating, untreatable motor neuron disease with unknown causes, but nutritional and lifestyle factors may play a role. To check this hypothesis, we conducted a multicentre ...
  • Clinical features and outcome in patients with Guillain-Barré syndrome 
    Lentitchii, Alina; Haider, Zeyba; Melnic, Adrian; Sangheli, Marina; Plesca, Svetlana; Simon, Victoria (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Guillain-Barré syndrome (GBS) is a heterogeneous group of autoimmune polyradiculopathies, in which disease biomarkers, and outcome predictors are under continuous research. Material and methods: Thirty-three ...
  • Imaging aspects in Spastic Cerebral Palsy in children 
    Cuznet, Ludmila; Hadjiu, Svetlana; Calcii, Cornelia; Griu, Corina; Racovita, Stela; Lupușor, Nadejda; Feghiu, Ludmila; Sprincean, Mariana; Revenco, Ninel (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Magnetic resonance imaging (MRI) is commonly used in the investigation of children with cerebral palsy (CP). This investigation suggests hope in future therapeutic interventions of children with CP. The aim ...
  • SARS-Cov-2 associated periferal neuropathy and congenital myopathy: case report 
    Rusu, Irina; Lisnic, Vitalie; Railean, Gheorghe (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Association of congenital myopathy with COVID-19 – associated peripheral neuropathy is not reported. We aim to present such a case. Material and methods: Clinical case of a 14-year-old male with history of ...
  • Results of the cohort study of cognitive impairment associated with Parkinson's disease 
    Rotaru, Lilia (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Cognitive impairment (CI) is frequent in Parkinson’s Disease (PD), having particular features. Material and methods: Sixty-five consecutive PD patients, (mean age 64.87 ± 7.69 y.o.; disease duration 50.21 ± ...
  • Evolution of status epilepticus in children 
    Calcii, Cornelia; Sprincean, Mariana; Lupușor, Nadejda; Griu, Corina; Cuznet, Ludmila; Racovita, Stela; Feghiu, Ludmila; Hadjiu, Svetlana (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Status epilepticus is defined as a neurologic emergency in which there is at least 5 minutes of continuous seizure activity or recurrent seizures with a return to baseline between seizures. The aim of this ...
  • Anxiety in epilepsy. Gender differences 
    Doten, Natalia (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The aim of the study was to assess the prevalence of anxiety symptoms in women and men with epilepsy, and to evaluate their relationships with psychological variables: duration of the epilepsy disease, education, ...
  • Four years’ experience of participation of the Republic of Moldova in the RES-Q Registry 
    Manole, Elena; Ciobanu, Natalia; Crivorucica, Igor; Odainic, Olesea; Lisnic, Vitalie; Zota, Eremei; Plotnicu, Sorin; Turcanu, Ghenadie; Harco, Ala; Cravcenco, Natalia; Cretu, Natalia; Todirean, Rodica; Dolghier, Valentina; Barbaros, Valentina; Crijanovschi, Svetlana; Eleniuc, Diana; Salcutanu, Veaceslav; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The Republic of Moldova is a member of the Registry of Stroke Care Quality (RES-Q) project, initiated by the European Stroke Organization in 2016. The aim of this study was to analyze the in-hospital stroke ...
  • Epidemiological data on Myasthenia gravis related to SARS-COV-2 infections in the Republic of Moldova 
    Lisnic, Vitalie; Bubuioc, Ana-Maria; Alboini, Paulo Emilio; Leone, Maurizio Angelo (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: The aim of this study is to provide an estimated incidence of Myasthenia Gravis (MG) and to describe the pattern of the disease in the Republic of Moldova before and during the COVID-19 pandemic. Material and ...
  • Prevalence and clinical peculiarities of Multiple Sclerosis in the Republic of Moldova 
    Belenciuc, Anna; Odainic, Olesea; Lisnic, Vitalie; Leone, Maurizio Angelo (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, neurodegenerative disease of the central nervous system and the most common disabling neurological disease in young adults. The disease natural ...
  • Objective assesment of sympathetic electrodermal activity in patients with masticatory muscle pain 
    Bordeniuc, Gheorghe; Lacusta, Victor; Fala, Valeriu (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Masticatory muscle pain is associated with autonomic disorders of different intensity; their identification leads to a more accurate diagnosis and a differentiated treatment. Currently, various scales and ...
  • Assessment of risk factors in post-stroke cognitive impairment 
    Gavriluta, Diana; Gasnas, Alexandru; Groppa, Stanislav (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Cognitive impairment is a frequent symptom in post-stroke patients, with a prevalence range of 20% to 80%. Our study’s aim was to analyze the previously reported risk factors in order to highlight predictors ...
  • The impact of the pandemic on the in – hospital stroke quality indicators based on the RES-Q Register 
    Serebreanschi, Elena; Manole, Elena; Odainic, Olesea; Lisnic, Vitalie (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: Coronavirus pandemic (COVID-19) has influenced not only global morbidity statistics, but also healthcare ones in relation to other diseases, including stroke. The aim of the study was to analyse the in-hospital ...
  • Anxiety and sympathetic skin responses in patients with masticatory muscle pain 
    Fala, Valeriu; Lacusta, Victor; Bordeniuc, Gheorghe (The Scientific Medical Association of the Republic of Moldova, 2021)
    Background: An important clinical aspect of masticatory muscle pain is its association with autonomic disorders and various mental states. Sympathetic skin response is a non-invasive approach for assessing sympathetic ...

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