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Neurological complications in children with COVID-19 infection

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dc.contributor.author Hadjiu, Svetlana
dc.contributor.author Calcii, Cornelia
dc.contributor.author Feghiu, Ludmila
dc.contributor.author Griu, Corina
dc.contributor.author Racovita, Stela
dc.contributor.author Lupușor, Nadejda
dc.contributor.author Cuznet, Ludmila
dc.contributor.author Sprincean, Mariana
dc.contributor.author Revenco, Ninel
dc.date.accessioned 2021-10-07T13:29:19Z
dc.date.available 2021-10-07T13:29:19Z
dc.date.issued 2021
dc.identifier.citation HADJIU, Svetlana, CALCII, Cornelia, FEGHIU, Ludmila, GRIU, Corina, RACOVITA, Stela, et al. Neurological complications in children with COVID-19 infection. In: The Moldovan Medical Journal. 2021, vol. 64, no 3 (Neuro Congress Issue), p. 40. ISSN 2537-6381.
dc.identifier.issn 2537-6381
dc.identifier.issn 2537-6373
dc.identifier.uri http://moldmedjournal.md/wp-content/uploads/2021/09/Congres-Neuro-2021-Spaltul-11.pdf
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/18105
dc.description.abstract Background: Many studies suggest a mild course of COVID-19 infection in children. Severe complications with nervous system involvement associated with thrombotic and neurodestructive phenomena are reported. The aims of the study were to analyze the type of neurological complications associated with COVID-19 infection in children and to establish any age-related correlations. Material and methods: A group of 67 children diagnosed with SARS-CoV2 was analyzed. The nervous system involvement was assessed by various diagnostic methods, such as EEG, CT and / or brain MRI, psychological counseling. The SPSS program was used for statistical analysis. Results: Nonspecific neurological complications were registered in 40 cases (53.7%). They included headache – 35%, myalgias – 22.5%, anosmia – 17.5%, behavioral disorders – 12.5%, neurotic anorexia – 7.5%, mental disorders – 5%. Specific neurological complications were registered in 27 cases (46.3%), out of which: leukoencephalitis – 25.9%, Status epilepticus – 14.8%, toxic encephalopathy – 14.8%, cerebellitis – 11%, stroke – 11%, polyradiculoneuropathy – 7.4% , uncontrolled epilepsy – 7.4%, inferior flaccid monoplegia – 1 case (3.7%), transverse cervical myelitis – 1 case. Combined pathologies (leukoencephalitis with mixed stroke and venous sinus thrombosis, impaired vision) were registered in 3 cases. Severe cases were predominantly found in young children – 19 (28.4%). Severe neurological consequences were registered in 17 children (25.4%). Conclusions: The SARS-CoV 2 virus affects the CNS in children and can sometimes begin with isolated CNS lesions. Young children are at higher risk of developing seizures, encephalopathy and other severe complications from SARS-CoV-2 infection. Further studies on COVID-19 infection are needed to elucidate the frequency of infection and disease forms in children population. en_US
dc.language.iso en en_US
dc.publisher The Scientific Medical Association of the Republic of Moldova en_US
dc.relation.ispartof The Moldovan Medical Journal en_US
dc.subject children en_US
dc.subject nervous system en_US
dc.subject complications en_US
dc.subject infection en_US
dc.subject Covid-19 en_US
dc.title Neurological complications in children with COVID-19 infection en_US
dc.type Other en_US


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