Systemic lupus eritematosus pulmonary affection

Abstract

Introduction: According to statistics the Systemic Lupus Erythematosus is the most frequent disease of connective tissue, it is a systemic autoimmune disease of unknown etiology that affects one or more organs, characterized by an evolution with successive bouts with various clinical symptoms and laboratory manifestations, with hypersecretion of autoantibodies. It is a condition of current and particular interest from several points: the high incidence of disease in the medical practice, the severity of clinical forms of SLE, extremely complex and various clinical aspects, which evolves from severe to subtle and atypical forms, whose diagnosis can not be explained only by means of immunobiological explorations. Objectives of the work: Elucidation of the exogenous and endogenous risk factors in the onset of pleural and pulmonary impairment in SLE patients in the study. Study of the clinical particularyties and assessment of diagnostical significance of laboratory parameters in patients with systemic lupus erythematosus. Corellational analysis of clinical manifestations of pulmonary paraclinical indices and efficacy in patients with SLE. Scientifical inovation of the obtained results: Scientifical inovation lies in deciphering certain etiopathogenic aspects, clinical, diagnostic methods and treatment principles of LUPSA erythematosus disease based on a clinical study analytically. In this analytical study were assessed overall and peculiarities of clinical laboratory changes in patients with systemic lupus erythematosus to them by the correlation index inerpreta organic damage of the disease. The theoretical importance and value of the work: The paper aims to highlight the proportion of cases with clinical and laboratory manifestations, which gives Pulmonary severity and tracking progress under treatment. SLE is a collagenosis manifested by both cutaneous and musculoskeletal impairmen, but also visceral, renal and pulmonary damage the nervous system dictates the evolution and prognosis.Through early detection and appropriate treatment setting, with regular monitoring, these developments may relieve severe in most situations. The material and research methods: In accordance with the purpose and the investigational objectives outlined was made a retrospective descriptive study conducted on a group of 54 patients, 35 showed impaired SLE and 19 patients treated in clinical pulmonary Republican Hospital and the Hospital "Sf.Treime". In this study were included 54 patients, treated stationary PMS .S.C.R and "Sf. Treime" in 2013-2014. Our results and discussion: Retrospective descriptive study was conducted to performance aspects: clinical course, diagnosis and treatment of lung injury, correlation incidence of systemic lupus erythematosus and pulmonary damage depending on age and sex.