Evolutive particularities of gastrointestinal stromal tumors (GISTs)

Abstract

Background: Nosocomial pneumonia (NP) remains to be in top of the hospital-acquired infections and leads with high mortality. The initial empiric therapy recommendations require modification based on knowledge of the main bacterial infection patterns and local antibiotic resistance which are specific for different clinical departments. Objectives: To determine the differences of aetiological pathogens of nosocomial pneumonia (NP) in patients of surgical and medical departments. Materials and methods: We have studied 58 cases of nosocomial pneumonia in patients from the Clinical Republican Hospital who met the criteria issued by Centers for Diseases Control and Prevention (CDC) and were divided in two groups: Group A (35 cases) from medical departments and Group B (23 cases) from surgical departments. In these groups the quantitative deep tracheal aspiration and sputum cultures were used to diagnose agents responsible for NP. Results: In most cases in both groups the sputum cultures were positive for two and more pathological agents: group A - 77,1% (27/35), group B - 86,9% (20/23). The main aetiological pathogens isolated in these groups you can see in Table 1. Conclusions: In our study we have found some statistically significant differences in aetiological agents isolated from patients with nosocomial pneumonia from surgical and medical departments. The so called ”non-nosocomial” agent as Str.viridans was more frequent isolated in group of the patients from medical departments, while the classical ’’nosocomial” bacteria (.Ps.aeruginosae and Acinetobacter spp.) are more common to cause nosocomial pneumonia in patients from surgical departments. We explain this result by the large number of invasive procedures made in surgical departments and by lengthy hospitalization in these departments, which can increase the risk of colonization with ’’nosocomial” bacteria.