Abstract:
Introduction: Back pain is a widespread problem, affecting a large part of the population.
About 70% of the population suffers from recurrent back pain and about 15% of population of
permanent form. The risk of recurrent back pain is very high (70-80%). 5 % of patients develop
chronic back pain which lasts more then three months.
Purpose and Objectives: Management evaluation of drug treatment in severe vertebrogenic
pain syndrome through argumentation of administration of drugs with analgesic properties in
medical practice in the country.
Results: I conducted a retrospective study analyzing indication sheets of 58 patients
diagnosed with vertebrogenic pain syndrome hospitalized in the Medical Department of the
Ministry of Internal Affairs, during the period 2013-2014. Of the 58 patients aged 17-66 years,
diagnosed with vertebral pathology with persistent, violent and chronic algyc syndrome, 32 were
men (55,17 % ) and 26 (44,83 %) women. In most patients, examined according to indication
sheets, the most frequently localization of pathologies with algyc syndrome was in the lumbar
region constituting 41 patients (70.68%), the neck -11 patients (18.96%) and rarely found in the
chest- six patients (10%.). According to the obtained results was determined that, in rural areas,
vertebrogene pathologies predominated in men (41,37%) and in woman (18,9%); while in urban
area results are reversed: women -25% and men -13.7%.
Of the 58 patients analyzed, 20 were treated conservatively and 38 underwent surgery. I
concluded that patients receiving conservative treatment most frequently were treated with the following
drugs: tolperisone (midocalm) 16 patients, diazepam 13, clodifen 11 patients, 7 gabapentin, diclofenac 6
patients. The mentioned drugs have been prescribed for more then 7-10 days.
Conclusion: - vertebrogenic pain syndrome incidence in urban area increases essentially
among women and in rural areas vertebrogenic pathologies are more common among men.
- Basic treatment of pain syndrome represent not only drugs with analgesic effect, also are
used central muscle relaxants, tranquilizers and non-steroidal anti-inflammatory drugs.
The treatment corresponds to national clinical protocol.
Description:
Department of Pharmacology and Clinical Pharmacology, State University of Medicine and Pharmacy “Nicolae Testemitanu”, Chisinau, Republic of Moldova