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dc.contributor.author Cotelea, Tamara
dc.contributor.author Lungu, Tatiana
dc.contributor.author Stati, Lilia
dc.contributor.author Arama, Efim
dc.date.accessioned 2019-06-22T13:04:27Z
dc.date.available 2019-06-22T13:04:27Z
dc.date.issued 2011
dc.identifier.citation COTELEA, Tamara, LUNGU, Tatiana STATI, Lilia, ARAMA, Efim. Analiza chimico-toxicologică a amitriptilinei. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 1: Probleme medico-biologice şi farmaceutice, pp.406-409. en_US
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/1846
dc.description Catedra Chimie farmaceutică şi toxicologică USMF „N.Testemiţanu” Catedra Biofizică, Informatică şi Fiziologia omului „N.Testemiţanu” en_US
dc.description.abstract There was elaborated optimum isolation and extraction conditions of amitriptiline from biological fluids. We used physico – chemical methods to identify amitriptiline: chromatography on a thin layer by utilizing four systems of solvents, spectrophotometrical method in UV, HPLC.The methods processed by us for in biological tests “in vitro” are specific and reproductive, and they are recommended for the study of amitriptiline in biological fluids. Au fost determinate condiţiile optime de izolare şi extragere a amitriptilinei din lichidele biologice Am aplicat metodele fizico-chimice de identificare a amitriptilinei: cromatografia pe strat subţire utilizând patru sisteme de solvenţi, metoda spectrofotometrică în UV, HPLC. Metodele prelucrate de noi pentru amitriptilină în probele biologice „in vitro” sunt specifice şi reproductive şi ele se recomandă pentru studierea amitriptilinei în lichidele biologice. en_US
dc.language.iso other en_US
dc.publisher CEP Medicina en_US
dc.subject.mesh Amitriptyline en_US
dc.subject.mesh Amitriptyline - toxicity en_US
dc.subject.mesh Amitriptyline - blood en_US
dc.subject.mesh Amitriptyline - isolation and purification en_US
dc.subject.mesh Chromatography, Thin Layer - methods en_US
dc.title Analiza chimico-toxicologică a amitriptilinei en_US
dc.title.alternative Chemico-toxicological analysis of amitriptiline en_US
dc.type Article en_US


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