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Features of pulmonary tuberculosis depending on the methods of screening

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dc.contributor.author Chiriac, Doina
dc.date.accessioned 2021-11-11T14:24:16Z
dc.date.available 2021-11-11T14:24:16Z
dc.date.issued 2014
dc.identifier.citation CHIRIAC, Doina. Features of pulmonary tuberculosis depending on the methods of screening. In: MedEspera: the 5th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2014, pp. 111-112. en_US
dc.identifier.uri http://repository.usmf.md/handle/20.500.12710/18472
dc.description Pneumophtysiology Chair, PI State Medicine and Pharmacy University „Nicolae Testemițanu”, Chișinău, Republic of Moldova en_US
dc.description.abstract Introduction: Epidemiological state of tuberculosis in Republic of Moldova rests tensioned, with unsignificant deviation. Global incidence of tuberculosis (new cases and relapses), registered in 2011 is 114,3/100.000 populations, 37,4% of cases been very contagious, 38,0% with extensive destructions. In 2001 our country adopted DOTS strategy, recommended by World Health Organization in the control of tuberculosis, engaging the detection of least 70% of new cases of pulmonary tuberculosis by microscopy of the smear. As consequence, increased the rate of extensive tuberculosis with bilateral localizations, with lung destructions and dissemination, with vital complications, followed by the reduction of treatment success rate and increased of early mortality rate. Purpose and Objectives: Assessment of clinical, microbiological and radiological features of severe infiltrative pulmonary tuberculosis within Directly Observed Treatment Short course chemotherapy strategy. Material and methods: A total amount of 95 new pulmonary severe forms of tuberculosis were investigated, including gender and age features, clinical aspects, microbiological results of Ziehl Neelson staining, culture on Lowenstein Yensen medium and drug sensibility testing, diagnostics of co-morbidities and results of blood count. Results: Men /female rate 1,5/1, average age 42,6 yrs, 68% were late detected (complaining more than 3 month from the onset), by general practitioner through the passive way. Intoxication sings revealed were: asthenia 99%, loss of weight 96%, loss of appetite 78%, nights sweats 67%, vesperal fever 45% cases. Broncho-pulmonary signs were established: cough 100%, muco-purulent expectorations 100%, thoracic pain 34%, hemoptysis 26% cases. Co-morbidities had 40% cases. Radiological aspects were established: bilateral localizations in 78% cases, extension to more than 3 pulmonary segments at 96% cases, all being in evolution phase, with destructions 98% and bronchogenic dissemination 87% cases. Microbiological analysis established smear positive results for Ziehl-Neelson staining in 83% cases, Lowenstein-Yensen culture being positive in 84% cases, showing any resistance to the first anti-tuberculosis drugs in 34% cases. Conclusions: Assessment of clinical, microbiological and radiological features of severe infiltrative pulmonary tuberculosis within DOTS strategy revealed its predominance in male sex, in economicaly and reproductible age. Late detection by passive way, with well defined clinical signs, showing bilateral and extensive lung localizations, with high degree of bacilli emission, confers continuous epidemiological danger on health population. All enumerated characteristics are the consequence of the implementation of DOTS strategy in the control of tuberculosis in our country. Innovative contribution: For the first time in R. Moldova was established the features of severe pulmonary tuberculosis, according DOTS strategy. en_US
dc.language.iso en en_US
dc.publisher Ministry of Health of the Republic of Moldova, State Medical and Pharmaceutical University Nicolae Testemitanu, Medical Students and Residents Association en_US
dc.relation.ispartof MedEspera: The 5th International Medical Congress for Students and Young Doctors, May 14-17, 2014, Chisinau, Republic of Moldova en_US
dc.subject tuberculosis en_US
dc.subject DOTS en_US
dc.subject management en_US
dc.title Features of pulmonary tuberculosis depending on the methods of screening en_US
dc.type Other en_US


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  • MedEspera 2014
    The 5th International Medical Congress for Students and Young Doctors, May 14-17, 2014

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