Abstract:
Introduction: Nature provides us with the most effective remedies that stimulate the
functioning of the human body. By knowing and using herbs in the formulation and dose
antioxidant fixed for each individual person, we can be more resistant to stress, focus and greater
power of concentration and mental activity. The aim was to evaluate research conducted medicinal
plants with antioxidant action, given the increasing incidence and prevalence of many diseases in
Moldova pathologies such as cardiovascular, endocrine and cancer are influenced by the presence
of oxidative processes.
Materials and methods: Medicinal plants with antioxidant activity were selected based on
scientific publications, species were identified by Flora Identification Manual for the Republic of
Moldova and reference pharmacopoeias. Were characterized antioxidant active principles
responsible for the action and assessed phytopreparations by State Drug Nomenclature Moldova:
vegetable drugs, medicinal species, phyto antioxidant action. Was evaluated, also, legal status on
their release from pharmacies (OTC / Rx) and their presence in pharmacies in Moldova.
Results: Antioxidants herbs that was evaluated contains: vitamins, flavonoids and tannins in
amounts large or small, exhibiting antioxidant by trapping free radicals. Antioxidants act by giving
electronic and completing the last layer of free radicals , which are not deficient in electrons, loses
its harmful action. Also, flavonoids potentiate the action of other antioxidants, including vitamins E,
A and C. We note that among medicinal plants with antioxidant action, rank: Rosa canina L.- 14
medicinal products, Taraxacum officinale Web. - 10, Phaseolus vulgaris L. - 6, Cynara scolimus L.
- 5, Vaccinium myrthillus L. - 4, Hippophae rhamnoides L. - 4, Cichorium intybus L. - 4, Centaurea
cyanus L. - 3, Potentilla erecta L. - 2 and Aronia melanocarpa - 1.
Conclusion: The revaluation result phytopreparations after Nomenclature, we find that in
6350 registered products, 53 exhibit antioxidant, of which: 2 vegetable products, 17 medicinal
species, 10 phytopreparations monocomponent and 24 phytopreparations multicomponent. After the
release status of the pharmacy, we find that 95% are part of the OTC, 5% is released under doctor's
prescription, and their presence in pharmacies is 53%.
Description:
Department of Pharmacognosy and Pharmaceutical Botany, State Medical and Pharmaceutical
University “Nicolae Testemitanu”, Chisinau, Republic of Moldova