Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 20-22 octombrie 2021: Abstract book: Recent submissions

  • Magnetic nanoparticles in the detection of SARS-CoV-2 virus 
    Fiodorova, Svetlana; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The new COVID-19 infection, caused by the SARS-CoV-2 virus, has hit the global health care system due to its rapid spread from person to person. A prompt and accurate detection method is crucial in detecting ...
  • Features of the COVID-19 patients hospitalised in the Municipal Hospital of Phthisiopneumology, Chisinau, Republic of Moldova 
    Ungurean, Andrei; Lesnic, Evelina; Malic, Alina; El Abiat, Gamil Ali; Osipov, Tatiana; Kulcitkaia, Stela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The evolution of the COVID-19 patients is characterized by the poliorganic involvement in 5% of the patients and with mild evolution in more than 2/3 affected patients. Objective of the study. The evaluation ...
  • Monoclonal antibodies in SARS-CoV-2 infection therapy 
    Ananco, Alexandru; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Immunotherapy has its potential in the treatment of various infectious diseases. Monoclonal antibodies (mAbs), in particular, represent a relatively new approach in the therapy of SARS-CoV-2 infection. Objective ...
  • New technologies in the development of anti-COVID-19 vaccines 
    Sîrbu, Inesa; Diug, Eugen; Ciobanu, Nicolae; Guranda, Diana; Ciobanu, Cristina; Anton, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The COVID-19 pandemic as presented unique challenges for the development of modern technologies for large-scale vaccine production. Such an urgent need for a new vaccine has led to a significant reduction in ...
  • Pharmacological properties of direct factor Xa inhibitors 
    Oboroc, Sandu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Severe and critical COVID-19 complications include embolism or pulmonary thrombosis, hypercoagulable state, following pathological mechanisms: activation of coagulation factors, decreased anticoagulant and ...
  • Characteristics of infiltrative pulmonary tuberculosis cases (Caseous pneumonia) 
    Rafe, Marian Mohammad (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Caseous pneumonia is included in acute progressive form of pulmonary tuberculosis which usually affects multiple segments, either unilaterally or bilaterally. The clinical picture of caseous pneumonia is ...
  • Perspectives for use of a new unsaturated derivative of 1,2,4–triazol with antifungal and antibacterial action–nitrotriazone 
    Drumea, Maria; Valica, Vladimir; Uncu, Livia; Macaev, Fliur; Crudu, Valeriu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. 1,2,4-triazole derivatives show increasing interest in the development of antifungal and antibacterial drugs. Due to their dipole character and ability to bind hydrogen, triazoles act as pharmacophores by ...
  • Sepsis: current challenges and new solutions based on modern technologies. A clinical management approach 
    Iapăscurtă, Victor; Belîi, Adrian (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: Despite high associated mortality and high treatment costs, sepsis remains difficult to diagnose, particularly viral sepsis in COVID-19 infection with bacterial coinfection. A recent supplement to sepsis ...
  • Application of ultrasound in patients with kidney diseases 
    Sabeena, Mohammed Suhail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The use of ultrasound in nephrology has been on the increase in recent years. Doctors are increasingly performing ultrasonography, which has applications including investigations of the kidneys and lower ...
  • Role of epicardial adipose tissue in the pathogenesis of atrial fibrillation 
    Ostap, Felicia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Clinical studies revealed the correlation between epicardial fat volume and atrial fibrillation risk.This fat depot located between the myocardium and the visceral pericardium, due to the proximity to the ...
  • Evaluation of the impact of work-related stress on anesthesiologists and intensive care physicians 
    Tăzlăvan, Tatiana; Popili, Mihail; Ambrosii, Tatiana; Feghiu, Iuliana (Universitatea de Stat de Medicină și Farmacie ”Nicolae Testemițanu” din Republica Moldova, 2021)
    Background: Work-related stress is a major problem for employees and society. It is the second most common work-related health problem and affects 40 millions people in the European Union. Objective of the study. The ...
  • Association of pulmonary tuberculosis and COVID-19 
    Gamaniuc, Marina; Veselovskaia, Ana; Vișnevschi, Anatolie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The World Health Organization (WHO) estimated in 2019 10 million cases of tuberculosis (TB) with 1.6 million deaths worldwide. Since 2020, COVID-19 is a respiratory disease that has spread globally with ...
  • Features of injection drug users diagnosed with tuberculosis 
    Cotelea, Eugeniu; Mahamid, Uday Amir (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Injection drug users (IDUs) are among of the high risk to be screened for TB annually in the Republic of Moldova. It is due to their features which maintain them to be hard-to-reach for detection, treatment ...
  • Calcifying pulmonary nodules – clue to an alternative diagnosis 
    Bradauțan, Adela; Calaraș, Diana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Considering the high burden of TB in our country, a calcifying lung nodule on a chest X ray or chest CT is traditionally interpreted as a TB sequela. In reality calcium accumulation in the lung parenchyma or ...
  • Selection of optimal parameters for the analysis of dioxoindolinone by the method of high pressure liquids chromatography 
    Ștefaneț, Tatiana; Chirița, Cornel; Valica, Vladimir (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Anxiety and depression are among the most common mental disorders worldwide. Thus, the search for and obtaining new compounds used in the treatment of mental disorders is an important research topic, as well ...
  • Principle of formulation of circadian release medicines 
    Ciobanu, Cristina; Guranda, Diana; Ciobanu, Nicolae; Diug, Eugen; Solonari, Rodica (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Rheumatoid arthritis is a chronic disease that causes inflammation of the joints and surrounding tissues. To anticipate morning joint stiffness, chrono-therapeutic systems have been designed that adjust the ...
  • Features of tuberculosis in labour migrants from Chisinau, the Republic of Moldova 
    Zaid, Lafee; Abadi, Ahmad Reyad (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. In high TB burden countries, such as Moldova, TB is mostly diagnosed in young people from high risk groups including the migrant workers. Objective of the study. The aim the assessment of the general ...
  • Particulars of diagnosis and surgical treatment of patients with Mirizzi syndrome 
    Cucu, Ivan; Hotineanu, Adrian; Ferdohleb, Alexandru; Cazac, Anatol; Cazacu, Dimitru (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background: Mirizzi syndrome (SM) is a late and rare complication in the evolution of gallstones, morphologically translated by compression of the hepato-choledochus with stricture formation at this level or cholecysto-biliary ...
  • Application of design of experiments in pharmaceutical analysis 
    Donici, Elena; Crețu, Dionisie (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The quality of a drug should be design during the analytical development. Design of experiments are widely used to determine the influence of factors on the output responses of analytical methods. There are ...
  • The erythrocytes’ catalase activity is influenced by Taraxacum officinale 
    Protopop, Svetlana; Fulga, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The cells developed a series of antioxidant agents, which protect against harmful effects of H2O2. Taraxacumofficinale F. H. Wigg (TO) represents an important source of biologically active substances, whose ...

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