Abstract:
Introduction:Glomerular filtration rate (GFR)- measures
how much blood is filtered by the kidneys each minute and
is considered as the best overall indicator for how well an
individual's kidneys are functioning at a given moment.
Purpose: To bring out the difference between estimation
of GFR via commonly used different methods and compare
them.
Material and methods:Study design - descriptive. WHO
information sources, scientific papers from the PubMed
database were studied using the selected keywords.
Results:Smith's classical technique for GFR assessment,
urinary clearance of inulin, remains the reference against
which alternative clearance techniques and filtration
indicators are assessed.
Conclusions: There are many methods used to measure the GFR, depending on the clinical application and
availability. Although using inulin is still the gold standard, due to being a cumbersome technique, clinicians usually
estimate the GFR using serum creatinine and/or cystatin C.
