Abstract:
Introduction. Nanotechnology in cosmetology offers
an extraordinary opportunity for the
future, being considered one of the
most promising trends. Currently in
the cosmetics industry, nano-sized
ingredients are used, which offer
better UV protection, a deeper
penetration of the skin, production of
long-lasting effects, etc.
Purpose. Study of dermatocosmetics nanoformulations
with hyaluronic acid.
Material and methods. Analytical synthesis of the
literature in the field of technology
for the production and use of
nanocosmetics.
Results. Nano-formulations improve the stability of
various cosmetic ingredients. By encapsulating
them in nanoparticles increase the efficiency and
stability of UV filters on the skin surface and the
penetration of active ingredients into the
epidermis. Hyaluronic acid is used in the form of
nano-molecular sodium hyaluronate, which is
better absorbed, and studies had shown that its
injection into the inner layers of the skin forms a
protective film that prevents water evaporation,
moisturizes, regenerates cells and reduces
wrinkles. Transferosomes have systems that
reach the deepest layers of the skin, being
effective in various skin applications. NP penetration (fig.1) is a highly controversial
topic among the scientific community for at
least two main reasons: 1) the toxicological
implications of nanotechnology; 2) the need
to disclose the role of nanomaterials as
carriers for enhancing the penetration of the
bioactive agent.
Conclusion. Nanotechnology is applied in the field of dermatocosmetics
and is currently considered the most advanced technology,
by using nanoparticles with hyaluronic acid in the form of
creams, nanoemulsions, transferosomes, serums, etc. The
cosmetics industry shows great interest in nanotechnology
applications, and the superior properties of nanomaterials
encourage research and development of innovative products.
Moreover, regulatory requirements in the field of cosmetics
are much less demanding than in the pharmaceutical sector,
which opens up many opportunities for nanocosmetics.
Description:
Department of Drug Technology, "Nicolae Testemitanu" SUMPh, Chisinau, Republic of Moldova
