Abstract:
Introduction
Migraine is a disorder of the multisensory integration of the somatosensory, visual, auditory,
olfactory stimuli, which can later cause various combinations of symptoms: headache,
photophobia, phonophobia, nausea/vomiting, osmophobia, which distinguish it from other
types of headaches.
Purpose
Highlighting the particularities of the pain phenomenon and the associated symptoms in
patients with migraine (frequency, duration and severity of the migraine symptoms).
Material and methods
94 patients with migraine were included in the cross-sectional study. Research methods used: clinical
(neurological history, objective neurological examination); descriptive (description of the results);
statistical (evaluation questionnaires for migraine patients were used as a research tool). The primary data
were introduced into Excel and processed in MedCalc.
Results
Positive correlations were identified between headache intensity and associated symptoms: nausea
(Rxy=+0.36, p<0.05), vomiting (Rxy=+0.25, p<0.05), photophobia (Rxy=+0.36, p<0.05), phonophobia
(Rxy=+0.52, p<0.0001), anxiety (Rxy=+0.24, p<0.05), panic (Rxy=+0.26, p<0.05). There were positive
correlations between the duration of the headache (attack) in hours and the symptoms associated with
migraine: anxiety (Rxy=+0.34, p<0.01), dysfunctional respiratory syndrome (Rxy=+0.33, p<0.01).
Statistically significant positive correlations were determined between headache intensity and pain
character: oppressive (Rxy=+0.28, p<0.05), stinging (Rxy=+0.24, p<0.05) and pulsing (Rxy=+0.24, p<0.05).
Conclusions
The presence and intensity of the migraine pain event was related to the presence and intensity of the
associated symptoms (photophobia, phonophobia, nausea, vomiting, anxiety and panic). Unlike intensity,
headache duration in hours correlated only with anxiety and dysfunctional respiratory syndrome. Pulsing
pain quality correlates positively with phonophobia. The results support the headache modular theory,
which shows that different neuron modules forming the clinical expression of migraine attacks can be
activated.
