Abstract:
Introduction: About 60% to 80% of all ischemic strokes can be attributed to increasing blood
pressure, blood cholesterol, smoking, diabetes mellitus and atrial fibrillation [American Heart
Association, June 29 2006; Potential New Risk Factors for Ischemic Stroke. What Is Their
Potential? Graeme J. Hankey]. Hypertension is the single most important modifiable risk factor for
ischemic stroke. Various lifestyle factors have been associated with increased stroke risk. These
include obesity, physical inactivity, diet, and acute triggers such as emotional stress. Obesity has
been associated with higher levels of blood pressure, blood glucose, and atherogenic serum lipids,
which are independent risk factors for stroke.
Materials and Methods: Our study included 50 patients with hypertension and cognitive
impairment, hospitalized in the cardiology department, Holy Trinity Hospital. We determined the
association between MMSE score and incident CV events, adjusted for stroke, diabetes mellitus,
atrial fibrillation, smoking and sedentary. We divided patients according to MMSE in 3 categories:
1. Lack of cognitive dysfunction: M M SE-24-30points;
2. Moderate cognitive dysfunction: M M SE-18-23points;
3. Severe cognitive dysfunction: 0-17points.
Maximum score for MMSE is 30 points.
The table shows that severe cognitive deficit is characteristic of patients with stroke,
sedentary, diabetes mellitus. Moderate cognitive dysfunction was characteristic for smoking
patients, diabetes mellitus and atrial fibrillation.
Conclusion: Doctors have long called high blood pressure “the silent killer” because a person can
have high blood pressure and never have any symptoms. Blood pressure is the most important risk factor
in the occurrence of stroke. In our study we tried to demonstrate the relationship between high blood
pressure and other risk factors involved in the occurrence stroke, and cognitive deficits caused by these.
Description:
Cardiology Department, State University
of Medicine and Pharmacy "Nicolae Testemitanu", Chisinau, Republic of Moldova