Abstract:
Introduction: Prenatal rupture of membranes is currently the most common disease of pregnancy
and it is dangerous for both mother and fetus. The three main causes of neonatal mortality associated
with prenatal rupture of membranes are the following: prematurity, sepsis, and pulmonary hypoplasia.
The risk for the mother is associated primarily with chorioamnionitis.
Purpose: To evaluate the perinatal outcome, etiological factors in prenatal rupture of membranes and
effectiveness of modern management.
Materials: We performed a retrospective analysis of 65 medical health records from the Regional
Perinatal Center in the city of Aktobe. Age ranged from 18 to 42 years.
DIOV reasons were the following: a history of chronic endometritis for 3-6 years -19 women (19%),
due to the previous prenatal rupture of membranes at delivery - 6 Women, 6 (%) due to an abortion - 48
women (48%), due to genital infections - 17 women (17%), due to extragenital disease - 10 (10%). Results: The analysis showed that the choice of expectant management of the prenatal rupture of
membranes at any stage of gestation has a positive effect on the pregnancy outcome for both mother and
fetus than active management of labor. Of the 67 infants, 14 (20.8%) were born at 33-37 weeks of gestation weighing 999-2500 grams, 53 (79.1%) were born at 37-41 weeks of gestation weighing 2500-4200
g, 91% of newborns were transferred to the Department of infants, 86% had spontaneous labor.
