Abstract:
Background: The selection and spreading of multidrug-resistant bacterial strains to antibiotics represents a current problem for the medical world due to irrational use of antimicrobial substances. An
important resistance mechanism at 13-lactamic antibiotics was developed by ESBL-bacterial strains (extended spectrum (3-lactamases bacterial strains), usually involved in nosocomial infections.
Patients and methods: The purpose of the clinical trial consisted in assessing the extended spectrum
(3- lactamases bacterial strains within Enterobacteria isolated from various samples taken from patients
who were hospitalized in the Emergency County Hospital in Brasov and also the distribution on the
hospital wards.
Results: The most often encountered germs were from the Enterobacteriaceae family (58.42%). The
main species found was Escherichia coli (70.52%), followed by Enterobacter spp. (10.87%), Klebsiella
spp. (10.11%), Proteus spp. (7.54%), Serratia spp. (0.65%), Citrobacter spp. (0.24%) and Morganella spp.
(0.07%). The biggest frequency of positive ESBL-bacterial strains was obtained in the case of E. coli
(52.45%), followed by Klebsiella spp. (23.77%), Enterobacter spp. (19.12%) and Proteus spp. (4.66%).
Conclusions: This study reveals monitoring necessity of multidrug-resistance to antibiotics in hospitals were this phenomenon is increasing and frightening.
