Abstract:
Introduction: Gastrointestinal autonomic nerve tumors (GANT) are a rare subgroup of gastrointestinal stromal tumors (GIST). Their histological appearance is similar to that of other GISTs. Up to date
only about 200 cases were published in English literature.
Aim: We report an additionally case of gastric GANT.
Methods: A 72 years old female patient was admitted with abdominal tumor mass which occurred
in the stomach according CT scan. She underwent a surgery and subtotal gastrectomy was performed.
Results: Postoperative recovery was uneventful. Histological examination and immunohistochemical
analysis revealed the diagnosis of a gastrointestinal autonomic nerve tumor. The immunohistochemical profile of the tumor revealed positive staining to c-kit (CD117), CD34, vimentin and S-100, positive
staining to neuron-specific enolase (NSE) and negative staining to desmin. Three months after initial
diagnosis and surgery the patient is asymptomatic and was scheduled for very close follow up.
Conclusion: Radical surgical resection of gastrointestinal autonomic nerve tumors seems to be the
only available curative approach to date in patients with no metastasis.
