Abstract:
Introduction: Postoperative Cognitive Dysfunction (POCD) is a decline of cognitive function that
occurs during the first days or few weeks after the surgery. POCD was mainly studied in elderly patients
after major surgery (cardiac and vascular surgery, joint replacement). The prevalence varies from 24% to
79%. There are only few studies concerning POCD in young adult patients. Also, there are no diagnostic
criteria for POCD. Goals and objectives: Comparative assessment of pre- and postoperative cognitive
performance in young adult patients after intermediate risk abdominal surgery. The ability to memorize
the numbers, working with numerical series, coding number-symbol, color stroop effect was particularly
appreciated.
Materials and Methods: It is a prospective study, being approved by the Ethic Committee. Written
informed consent, to participate in the study, was obtained from 17 young adult patients (>18 years).
Patients were admitted to National Scientific and Practical Centre of Emergency Medicine to be subject
to abdominal surgery. All patients were assessed pre- and postoperatively using 5 tests:
1. Mini Mental Status (MMS); 2. Digit Span Test (DST); 3. Digit Connection Test (DCT); 4. Digit
Symbol Substitution Test (DSST); 5. Reedley Color Stroop Test (RCST).
Results: The following results were obtained.
MMS: 28,0 (95CI 26,72-29,28) vs. 28,19 (95CI 26,95-29,42), p=0,92.
DST: 8,75 (95CI 8,15-9,35) vs. 9,13 (95CI 8,23-10,0), p=0,27.
DCT: 35,03 (95CI 28,26-41,80) vs. 30,12 (95CI 24,80-35,43), p=0,0564.
DSST: 37,50 (95CI 32,04-42,96) vs. 39,38 (95CI 33,52-45,23), p=0,18.
RCST: 19,77 (95CI 17,77-21,76) vs. 19,43 (95CI 16,19-22,67), p=0,77.
Conclusion: Cognitive status of young adult patients after abdominal surgery is not affected by anesthesia or surgery on the 4th - 7th day. Some particular aspects of cognitive function (working with numerical series, symbol decoding) seem to be affected by anesthesia or surgery (borderline statistical significance).
