Primary tumors of jejunum and ileum: one center experience

Abstract

Introduction: Primary benign and malignant tumors of jejunum and ileum are rare. They are very often diagnosed by accident or as a cause of acute abdomen. Purpose: The aim of study was to analyze the cases of primary tumors of jejunum and ileum admitted for surgical procedures in an emergency and elective setting. Materials and Methods: Retrospective review of all patients referred to our institution and diagnosed with primary tumors of jejunum and ileum and its complications during the last 7 years. Results: There were 15 pts (F-9, M-6) with mean age of 52.9 ±5.1 years (range from 17 to 79). Intussusceptions (n=6), intestinal obstruction (n=3), perforation (n=2), intussusceptions/ perforation with GI bleeding (n=2) were the most common clinical presentations. In 2 cases primary tumors of jejunum and ileum were detected as incidental findings during surgical procedure. Most tumors (n = ll, 73.3%) were located in the ileum. In 15 pts intestinal resection (R()-12, R ,-l) with end-to-end (n=7), side-to-side (n=6), Maydl procedure (n=l) and terminal ileostomy (n=l) were performed. There were 9 benign tumors (leiomyoma-4, angioleiomyoma- 2, fibrolipoma -2, fibroid polyp-1) and 6 malignant (c-KIT/CD 117 positive GISTs-2, lymphomas-2, neuroendocrine tumor-1, adenocarcinoma-1). Conclusion: Primary tumors of jejunum and ileum are rare, the symptoms often non-specific, and the accuracy of different diagnostic tests needs to be improved. Timing and type of the intervention to the process and biological behavior of the pathological cells predict the prognosis.