Abstract:
Introduction. Cardiovascular diseases are the main
cause of mortality and morbidity in the
general population. Idiopathic
inflammatory myopathies are
characterized both by skeletal muscle
inflammation and visceral damage, the
heart being one of the frequently
affected organs thus presenting risk of
cardiovascular diseases.
Purpose. Outlining the traditional and non-traditional
cardiovascular risk factors in idiopathic
inflammatory myopathies.
Material and methods. Data from scientific literature was selected and
reviewed using data based such as PubMed,
Frontiers, Scientific Research, NIH, BMJ Journals.
Results. By analyzing the data from scientific literature
it was established that the most frequent
traditional cardiovascular risk factors are
dyslipidemia, obesity and hypertension. The
non-traditional ones were autoimmune
inflammation and endothelial dysfunction
with accelerated plaque formation. The
concomitant influence of these two groups of
factors aggravates the properties and function
of arterial vessels consequently leading to high
cardiovascular morbidity and mortality.
Conclusions. Traditional and non-traditional
cardiovascular risk factors precipitate and
aggravates cardiovascular involvement in
patients with idiopathic inflammatory
myopathies leading to increased mortality
and morbidity. Knowledge of this data is
crucial for prevention and management of
cardiac involvement
