Abstract:
Introduction.
Passive detection of symptomatic patients
leads to the diagnosis of severe, extensive
and late detected forms which have more
frequently unfavourbale treatment
outcome.
Purpose.
To assess the clinical features of patients
with late-detected pulmonary tuberculosis
(PTB).
Material and methods.
A longitudinal, selective study which evaluated the features of 92
patients registered with late detected PTB in Chisinau during 2019 was
conducted, including 56 (61%) caseous pneumonia and 36 (39%)
lobitis. Including criteria: age > 18 years, diagnosed with late detected
PTB, hospitalized in the Municipal Hospital of Phthisiopneumology, in
2019, signed informed agreement. Excluding criteria: age <18 years,
diagnosed with another localization, timely detected, hospitalized in
other institutions, other period 2019, absence of the signed consent.
Results.
The insidious onset 1-3 months was in 65(71%), 90-120 days in
11(12%) and 4+ months in 16(17%) cases. Cough with muco-purulent
sputum in all cases, 34(36%) - dyspnea, 21 (23%) - chest pain,
17(18%) - hemoptysis, 10(11%)- pulmonary hemorrhage, 88(95%)-
anorexia, 5(5%)-cachexia. Passively detected by the general
practitioner were 43(46%), through screening 12(13%), passively
detected by specialists-15(16%) and through screening 10(18%)
patients. 12(13%) through emergency. Therapeutic success was
established in 34(37%), 42(45%) died and 16(18%) failed.
Conclusion. The peculiarities of patients with late detected TBP were:
insidious onset, clinical expressiveness that were determined by
passive detection and resulted in a low therapeutic success rate and
high death rate.
